{"id":300,"date":"2019-11-04T23:42:13","date_gmt":"2019-11-04T23:42:13","guid":{"rendered":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/chapter\/7-2-basic-concepts-of-the-gastrointestinal-system\/"},"modified":"2025-01-16T22:27:34","modified_gmt":"2025-01-16T22:27:34","slug":"7-2-basic-concepts-of-the-gastrointestinal-system","status":"publish","type":"chapter","link":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/chapter\/7-2-basic-concepts-of-the-gastrointestinal-system\/","title":{"raw":"7.2 Basics Concepts of the Gastrointestinal System","rendered":"7.2 Basics Concepts of the Gastrointestinal System"},"content":{"raw":"<div class=\"1.2-basics:-gastrointestinal-system-review-\">\n\nPrior to discussing specific GI disorders and associated medication classes, it is important to have a clear understanding of the anatomy the gastrointestinal system.\n<h2>Review of Anatomy of the Gastrointestinal System<\/h2>\nIt is important to know the basic anatomy and physiology of the gastrointestinal system to understand how gastrointestinal (GI) medications work. See Figure 7.1<sup>[footnote]\u201c<a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:2401_Components_of_the_Digestive_System.jpg\" target=\"_blank\" rel=\"noopener noreferrer\">Components of the Digestive System<\/a>\u201d by <a href=\"https:\/\/cnx.org\/\" target=\"_blank\" rel=\"noopener noreferrer\">CNX OpenStax<\/a> is licensed under <a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">CC BY 4.0<\/a>. Access for free at <a href=\"https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/23-1-overview-of-the-digestive-system\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/23-1-overview-of-the-digestive-system<\/a>[\/footnote]<\/sup> for an illustration of the anatomical components of the GI system. There are a variety of medications used to treat common GI disorders, so this chapter's content is divided into three subsections discussing medications classes treating common disorders: antiulcer, antidiarrheals\/laxatives, and antiemetics. Each subsection will further review the GI anatomy and physiology related to these conditions and medications.\n\n[caption id=\"\" align=\"aligncenter\" width=\"570\"]<img title=\"&quot;Components of the Digestive System&quot; by CNX OpenStax is licensed under CC BY 4.0 Access for free at https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/23-1-overview-of-the-digestive-system\" src=\"https:\/\/pressbooks.ccconline.org\/accdigitalmarketing\/wp-content\/uploads\/sites\/219\/2019\/11\/image1.png\" alt=\"Illustrations showing labeled components of the GI system on a human torso\" width=\"570\" height=\"722\"> Figure 7.1 Components of GI System[\/caption]\n\n<div class=\"textbox\">\n\nFor additional details related to the content in this chapter, review information in OpenStax <em>Anatomy and Physiology<\/em> using the areas noted below<sup>[footnote]This work is a derivative of <a href=\"https:\/\/openstax.org\/details\/books\/anatomy-and-physiology\" target=\"_blank\" rel=\"noopener noreferrer\">Anatomy and Physiology<\/a> by <a href=\"https:\/\/openstax.org\/\" target=\"_blank\" rel=\"noopener noreferrer\">OpenStax<\/a> licensed under <a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">CC BY 4.0<\/a>. Access for free at <a href=\"https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/1-introduction\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/1-introduction<\/a>[\/footnote]:<\/sup>\n\n<a class=\"arrow\" href=\"https:\/\/cnx.org\/contents\/FPtK1zmh@16.5:lPvBytyq@8\/23-1-Overview-of-the-Digestive-System\" target=\"_blank\" rel=\"noopener noreferrer\">Overview of the Digestive System<\/a>\n\n<a class=\"arrow\" href=\"https:\/\/cnx.org\/contents\/FPtK1zmh@16.5:r-g7Ewwc@9\/23-2-Digestive-System-Processes-and-Regulation\" target=\"_blank\" rel=\"noopener noreferrer\">Digestive System Processes and Regulation<\/a>\n\n<a class=\"arrow\" href=\"https:\/\/cnx.org\/contents\/FPtK1zmh@16.5:O9dvCxUQ@8\/23-4-The-Stomach\" target=\"_blank\" rel=\"noopener noreferrer\">The Stomach<\/a>\n\n<a class=\"arrow\" href=\"https:\/\/cnx.org\/contents\/FPtK1zmh@16.5:Qw2OWvaZ@9\/23-5-The-Small-and-Large-Intestines\" target=\"_blank\" rel=\"noopener noreferrer\">The Small and Large Intestines<\/a>\n\n<a class=\"arrow\" href=\"https:\/\/cnx.org\/contents\/FPtK1zmh@16.5:mpJrhmfQ@12\/23-7-Chemical-Digestion-and-Absorption-A-Closer-Look\" target=\"_blank\" rel=\"noopener noreferrer\">Chemical Digestion and Absorption: A Closer Look<\/a>\n\n<\/div>\n&nbsp;\n<div class=\"textbox\">\n<p style=\"text-align: left\">See the following supplementary YouTube videos to review the gastrointestinal system and digestive processes.<\/p>\n\n<h3 class=\"video\">Gastrointestinal System Review<sup>[footnote]Forciea, B. (2015, March 18). <em>Anatomy and physiology of the digestive system<\/em> [Video]. YouTube. All rights reserved. Video used with permission. <a href=\"https:\/\/youtu.be\/1ssJV-EpfiQ\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/youtu.be\/1ssJV-EpfiQ<\/a>\u00a0[\/footnote]<\/sup><\/h3>\n[embed]https:\/\/www.youtube.com\/watch?v=1ssJV-EpfiQ[\/embed]\n<h3 class=\"video\"><a href=\"https:\/\/youtu.be\/Og5xAdC8EUI\" target=\"_blank\" rel=\"noopener\">Ted Ed Review of Digestive System<\/a><sup>[footnote]Bryce, E. (2017, December 14). <em>How your digestive system works<\/em>\u00a0[YouTube]. All rights reserved. <a href=\"https:\/\/youtu.be\/Og5xAdC8EUI\">https:\/\/youtu.be\/Og5xAdC8EUI<\/a>\u00a0[\/footnote]<\/sup><\/h3>\n<h3 class=\"video\"><a href=\"https:\/\/www.khanacademy.org\/science\/health-and-medicine\/gastro-intestinal-system\/gastrointestinal-intro\/v\/meet-the-gastrointestinal-tract\" target=\"_blank\" rel=\"noopener noreferrer\">Khan Academy Review of GI System<\/a><sup>[footnote]\u201c<a href=\"https:\/\/www.khanacademy.org\/science\/health-and-medicine\/gastro-intestinal-system\/gastrointestinal-intro\/v\/meet-the-gastrointestinal-tract\" target=\"_blank\" rel=\"noopener noreferrer\">Meet the Gastrointestinal Tract!<\/a>\u201d by Raja Narayan is licensed under<a href=\"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/\" target=\"_blank\" rel=\"noopener noreferrer\"> CC BY-NC-SA 3.0<\/a>[\/footnote]<\/sup><\/h3>\n<\/div>\n<\/div>","rendered":"<div class=\"1.2-basics:-gastrointestinal-system-review-\">\n<p>Prior to discussing specific GI disorders and associated medication classes, it is important to have a clear understanding of the anatomy the gastrointestinal system.<\/p>\n<h2>Review of Anatomy of the Gastrointestinal System<\/h2>\n<p>It is important to know the basic anatomy and physiology of the gastrointestinal system to understand how gastrointestinal (GI) medications work. See Figure 7.1<sup><a class=\"footnote\" title=\"\u201cComponents of the Digestive System\u201d by CNX OpenStax is licensed under CC BY 4.0. Access for free at https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/23-1-overview-of-the-digestive-system\" id=\"return-footnote-300-1\" href=\"#footnote-300-1\" aria-label=\"Footnote 1\"><sup class=\"footnote\">[1]<\/sup><\/a><\/sup> for an illustration of the anatomical components of the GI system. There are a variety of medications used to treat common GI disorders, so this chapter&#8217;s content is divided into three subsections discussing medications classes treating common disorders: antiulcer, antidiarrheals\/laxatives, and antiemetics. Each subsection will further review the GI anatomy and physiology related to these conditions and medications.<\/p>\n<figure style=\"width: 570px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" title=\"&quot;Components of the Digestive System&quot; by CNX OpenStax is licensed under CC BY 4.0 Access for free at https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/23-1-overview-of-the-digestive-system\" src=\"https:\/\/pressbooks.ccconline.org\/accdigitalmarketing\/wp-content\/uploads\/sites\/219\/2019\/11\/image1.png\" alt=\"Illustrations showing labeled components of the GI system on a human torso\" width=\"570\" height=\"722\" \/><figcaption class=\"wp-caption-text\">Figure 7.1 Components of GI System<\/figcaption><\/figure>\n<div class=\"textbox\">\n<p>For additional details related to the content in this chapter, review information in OpenStax <em>Anatomy and Physiology<\/em> using the areas noted below<sup><a class=\"footnote\" title=\"This work is a derivative of Anatomy and Physiology by OpenStax licensed under CC BY 4.0. Access for free at https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/1-introduction\" id=\"return-footnote-300-2\" href=\"#footnote-300-2\" aria-label=\"Footnote 2\"><sup class=\"footnote\">[2]<\/sup><\/a>:<\/sup><\/p>\n<p><a class=\"arrow\" href=\"https:\/\/cnx.org\/contents\/FPtK1zmh@16.5:lPvBytyq@8\/23-1-Overview-of-the-Digestive-System\" target=\"_blank\" rel=\"noopener noreferrer\">Overview of the Digestive System<\/a><\/p>\n<p><a class=\"arrow\" href=\"https:\/\/cnx.org\/contents\/FPtK1zmh@16.5:r-g7Ewwc@9\/23-2-Digestive-System-Processes-and-Regulation\" target=\"_blank\" rel=\"noopener noreferrer\">Digestive System Processes and Regulation<\/a><\/p>\n<p><a class=\"arrow\" href=\"https:\/\/cnx.org\/contents\/FPtK1zmh@16.5:O9dvCxUQ@8\/23-4-The-Stomach\" target=\"_blank\" rel=\"noopener noreferrer\">The Stomach<\/a><\/p>\n<p><a class=\"arrow\" href=\"https:\/\/cnx.org\/contents\/FPtK1zmh@16.5:Qw2OWvaZ@9\/23-5-The-Small-and-Large-Intestines\" target=\"_blank\" rel=\"noopener noreferrer\">The Small and Large Intestines<\/a><\/p>\n<p><a class=\"arrow\" href=\"https:\/\/cnx.org\/contents\/FPtK1zmh@16.5:mpJrhmfQ@12\/23-7-Chemical-Digestion-and-Absorption-A-Closer-Look\" target=\"_blank\" rel=\"noopener noreferrer\">Chemical Digestion and Absorption: A Closer Look<\/a><\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<div class=\"textbox\">\n<p style=\"text-align: left\">See the following supplementary YouTube videos to review the gastrointestinal system and digestive processes.<\/p>\n<h3 class=\"video\">Gastrointestinal System Review<sup><a class=\"footnote\" title=\"Forciea, B. (2015, March 18). Anatomy and physiology of the digestive system [Video]. YouTube. All rights reserved. Video used with permission. https:\/\/youtu.be\/1ssJV-EpfiQ\u00a0\" id=\"return-footnote-300-3\" href=\"#footnote-300-3\" aria-label=\"Footnote 3\"><sup class=\"footnote\">[3]<\/sup><\/a><\/sup><\/h3>\n<p><iframe loading=\"lazy\" id=\"oembed-1\" title=\"Anatomy and Physiology of the Digestive System\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/1ssJV-EpfiQ?feature=oembed&#38;rel=0&#38;rel=0\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<h3 class=\"video\"><a href=\"https:\/\/youtu.be\/Og5xAdC8EUI\" target=\"_blank\" rel=\"noopener\">Ted Ed Review of Digestive System<\/a><sup><a class=\"footnote\" title=\"Bryce, E. (2017, December 14). How your digestive system works\u00a0[YouTube]. All rights reserved. https:\/\/youtu.be\/Og5xAdC8EUI\u00a0\" id=\"return-footnote-300-4\" href=\"#footnote-300-4\" aria-label=\"Footnote 4\"><sup class=\"footnote\">[4]<\/sup><\/a><\/sup><\/h3>\n<h3 class=\"video\"><a href=\"https:\/\/www.khanacademy.org\/science\/health-and-medicine\/gastro-intestinal-system\/gastrointestinal-intro\/v\/meet-the-gastrointestinal-tract\" target=\"_blank\" rel=\"noopener noreferrer\">Khan Academy Review of GI System<\/a><sup><a class=\"footnote\" title=\"\u201cMeet the Gastrointestinal Tract!\u201d by Raja Narayan is licensed under CC BY-NC-SA 3.0\" id=\"return-footnote-300-5\" href=\"#footnote-300-5\" aria-label=\"Footnote 5\"><sup class=\"footnote\">[5]<\/sup><\/a><\/sup><\/h3>\n<\/div>\n<\/div>\n<hr class=\"before-footnotes clear\" \/><div class=\"footnotes\"><ol><li id=\"footnote-300-1\">\u201c<a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:2401_Components_of_the_Digestive_System.jpg\" target=\"_blank\" rel=\"noopener noreferrer\">Components of the Digestive System<\/a>\u201d by <a href=\"https:\/\/cnx.org\/\" target=\"_blank\" rel=\"noopener noreferrer\">CNX OpenStax<\/a> is licensed under <a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">CC BY 4.0<\/a>. Access for free at <a href=\"https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/23-1-overview-of-the-digestive-system\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/23-1-overview-of-the-digestive-system<\/a> <a href=\"#return-footnote-300-1\" class=\"return-footnote\" aria-label=\"Return to footnote 1\">&crarr;<\/a><\/li><li id=\"footnote-300-2\">This work is a derivative of <a href=\"https:\/\/openstax.org\/details\/books\/anatomy-and-physiology\" target=\"_blank\" rel=\"noopener noreferrer\">Anatomy and Physiology<\/a> by <a href=\"https:\/\/openstax.org\/\" target=\"_blank\" rel=\"noopener noreferrer\">OpenStax<\/a> licensed under <a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">CC BY 4.0<\/a>. Access for free at <a href=\"https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/1-introduction\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/1-introduction<\/a> <a href=\"#return-footnote-300-2\" class=\"return-footnote\" aria-label=\"Return to footnote 2\">&crarr;<\/a><\/li><li id=\"footnote-300-3\">Forciea, B. (2015, March 18). <em>Anatomy and physiology of the digestive system<\/em> [Video]. YouTube. All rights reserved. Video used with permission. <a href=\"https:\/\/youtu.be\/1ssJV-EpfiQ\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/youtu.be\/1ssJV-EpfiQ<\/a>\u00a0 <a href=\"#return-footnote-300-3\" class=\"return-footnote\" aria-label=\"Return to footnote 3\">&crarr;<\/a><\/li><li id=\"footnote-300-4\">Bryce, E. (2017, December 14). <em>How your digestive system works<\/em>\u00a0[YouTube]. All rights reserved. <a href=\"https:\/\/youtu.be\/Og5xAdC8EUI\">https:\/\/youtu.be\/Og5xAdC8EUI<\/a>\u00a0 <a href=\"#return-footnote-300-4\" class=\"return-footnote\" aria-label=\"Return to footnote 4\">&crarr;<\/a><\/li><li id=\"footnote-300-5\">\u201c<a href=\"https:\/\/www.khanacademy.org\/science\/health-and-medicine\/gastro-intestinal-system\/gastrointestinal-intro\/v\/meet-the-gastrointestinal-tract\" target=\"_blank\" rel=\"noopener noreferrer\">Meet the Gastrointestinal Tract!<\/a>\u201d by Raja Narayan is licensed under<a href=\"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/\" target=\"_blank\" rel=\"noopener noreferrer\"> CC BY-NC-SA 3.0<\/a> <a href=\"#return-footnote-300-5\" class=\"return-footnote\" aria-label=\"Return to footnote 5\">&crarr;<\/a><\/li><\/ol><\/div>","protected":false},"author":83,"menu_order":2,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[48],"contributor":[],"license":[],"class_list":["post-300","chapter","type-chapter","status-publish","hentry","chapter-type-numberless"],"part":296,"_links":{"self":[{"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/300","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/wp\/v2\/users\/83"}],"version-history":[{"count":1,"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/300\/revisions"}],"predecessor-version":[{"id":301,"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/300\/revisions\/301"}],"part":[{"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/parts\/296"}],"metadata":[{"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/300\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/wp\/v2\/media?parent=300"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/chapter-type?post=300"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/wp\/v2\/contributor?post=300"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/wp\/v2\/license?post=300"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}