{"id":213,"date":"2019-11-12T17:52:43","date_gmt":"2019-11-12T17:52:43","guid":{"rendered":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/chapter\/5-9-expectorants\/"},"modified":"2025-01-16T22:26:02","modified_gmt":"2025-01-16T22:26:02","slug":"5-9-expectorants","status":"publish","type":"chapter","link":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/chapter\/5-9-expectorants\/","title":{"raw":"5.9 Expectorants","rendered":"5.9 Expectorants"},"content":{"raw":"Guaifenesin is an example of an expectorant.\n\n<strong>Mechanism of Action: <\/strong>Expectorants reduce the viscosity of tenacious secretions by irritating the gastric vagal receptors that stimulate respiratory tract fluid, thus increasing the volume but decreasing the viscosity of respiratory tract secretions.\n\n<strong>Indications:\u00a0<\/strong>Expectorants are used for a productive cough and for loosening mucus from the respiratory tract.\n\n<strong>Nursing Considerations: <\/strong>Avoid in children under the age of four. Guaifenesin is only recommended for use during pregnancy and breastfeeding when benefit outweighs the risk.\n\n<strong>Side Effects\/Adverse Effects: <\/strong>Guaifenesin may cause a skin rash, headache, nausea, and vomiting.<sup>[footnote]Frandsen, G., &amp; Pennington, S. (2018). <em>Abrams\u2019 clinical drug: Rationales for nursing practice <\/em>(11th ed.). Wolters Kluwer.[\/footnote]<\/sup>\n\n<strong>Health Teaching &amp; Health Promotion: <\/strong>Clients should take care to avoid irritants that stimulate their cough. Additionally, the medication can cause drowsiness. Clients should avoid taking them with other CNS depressants or alcohol.<sup>[footnote]uCentral from Unbound Medicine. <a href=\"https:\/\/www.unboundmedicine.com\/ucentral\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.unboundmedicine.com\/ucentral<\/a>[\/footnote]<\/sup> Encourage increased fluid intake to thin secretions, if not contraindicated.\n\nNow let's take a closer look at the medication grid for guaifenesin in Table 5.9.<sup>[footnote]This work is a derivative of\u00a0<a href=\"https:\/\/www.oercommons.org\/authoring\/54330-pharmacology-notes-nursing-implications-for-clinic\/view\" target=\"_blank\" rel=\"noopener noreferrer\">Pharmacology Notes: Nursing Implications for Clinical Practice<\/a>\u00a0by\u00a0<a href=\"https:\/\/www.oercommons.org\/profile\/213497\" target=\"_blank\" rel=\"noopener noreferrer\">Gloria Velarde<\/a>\u00a0licensed under\u00a0<a href=\"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">CC BY-NC-SA 4.0<\/a>[\/footnote],[footnote]Frandsen, G., &amp; Pennington, S. (2018). <em>Abrams\u2019 clinical drug: Rationales for nursing practice\u00a0<\/em>(11th ed.). Wolters Kluwer.[\/footnote],[footnote]This work is a derivative of\u00a0<a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/\" target=\"_blank\" rel=\"noopener noreferrer\">DailyMed<\/a>\u00a0by\u00a0<a href=\"https:\/\/www.nlm.nih.gov\/\" target=\"_blank\" rel=\"noopener noreferrer\">U.S. National Library of Medicine<\/a> in the <a href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/\" target=\"_blank\" rel=\"noopener noreferrer\">Public Domain<\/a>. [\/footnote]<\/sup>\n\nTable 5.9 Guaifenesin Medication Grid\n<table class=\"grid\" border=\"0\">\n<tbody>\n<tr>\n<th class=\"shaded\" style=\"width: 132.063px\" scope=\"col\">\n<h5><strong>Class\/Subclass<\/strong><\/h5>\n<\/th>\n<th class=\"shaded\" style=\"width: 165.063px\" scope=\"col\">\n<h5><strong>Prototype\/Generic<\/strong><\/h5>\n<\/th>\n<th class=\"shaded\" style=\"width: 382.063px\" scope=\"col\">\n<h5><strong>Nursing Considerations<\/strong><\/h5>\n<\/th>\n<th class=\"shaded\" style=\"width: 369.063px\" scope=\"col\">\n<h5><strong>Therapeutic Effects<\/strong><\/h5>\n<\/th>\n<th class=\"shaded\" style=\"width: 252.063px\" scope=\"col\">\n<h5><strong>Side\/Adverse Effects<\/strong><\/h5>\n<\/th>\n<\/tr>\n<tr>\n<th style=\"width: 132.063px\" scope=\"row\">Expectorant<\/th>\n<td style=\"width: 165.063px\"><a class=\"arrow\" href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=259c8b69-c625-4146-b888-34ef43b8385f\" target=\"_blank\" rel=\"noopener noreferrer\">guaifenesin<\/a><\/td>\n<td style=\"width: 382.063px\">No eating or drinking for 30 minutes after syrup\n\nEncourage client to cough and deep breathe\n\nEncourage increased fluid intake to thin secretions, if not contraindicated<\/td>\n<td style=\"width: 369.063px\">Helps loosen sputum (mucus) and thin bronchial secretions to make coughs more productive<\/td>\n<td style=\"width: 252.063px\">Increased drowsiness in large doses\n\nGastrointestinal: Nausea, vomiting, and diarrhea<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n&nbsp;","rendered":"<p>Guaifenesin is an example of an expectorant.<\/p>\n<p><strong>Mechanism of Action: <\/strong>Expectorants reduce the viscosity of tenacious secretions by irritating the gastric vagal receptors that stimulate respiratory tract fluid, thus increasing the volume but decreasing the viscosity of respiratory tract secretions.<\/p>\n<p><strong>Indications:\u00a0<\/strong>Expectorants are used for a productive cough and for loosening mucus from the respiratory tract.<\/p>\n<p><strong>Nursing Considerations: <\/strong>Avoid in children under the age of four. Guaifenesin is only recommended for use during pregnancy and breastfeeding when benefit outweighs the risk.<\/p>\n<p><strong>Side Effects\/Adverse Effects: <\/strong>Guaifenesin may cause a skin rash, headache, nausea, and vomiting.<sup><a class=\"footnote\" title=\"Frandsen, G., &amp; Pennington, S. (2018). Abrams\u2019 clinical drug: Rationales for nursing practice (11th ed.). Wolters Kluwer.\" id=\"return-footnote-213-1\" href=\"#footnote-213-1\" aria-label=\"Footnote 1\"><sup class=\"footnote\">[1]<\/sup><\/a><\/sup><\/p>\n<p><strong>Health Teaching &amp; Health Promotion: <\/strong>Clients should take care to avoid irritants that stimulate their cough. Additionally, the medication can cause drowsiness. Clients should avoid taking them with other CNS depressants or alcohol.<sup><a class=\"footnote\" title=\"uCentral from Unbound Medicine. https:\/\/www.unboundmedicine.com\/ucentral\" id=\"return-footnote-213-2\" href=\"#footnote-213-2\" aria-label=\"Footnote 2\"><sup class=\"footnote\">[2]<\/sup><\/a><\/sup> Encourage increased fluid intake to thin secretions, if not contraindicated.<\/p>\n<p>Now let&#8217;s take a closer look at the medication grid for guaifenesin in Table 5.9.<sup><a class=\"footnote\" title=\"This work is a derivative of\u00a0Pharmacology Notes: Nursing Implications for Clinical Practice\u00a0by\u00a0Gloria Velarde\u00a0licensed under\u00a0CC BY-NC-SA 4.0\" id=\"return-footnote-213-3\" href=\"#footnote-213-3\" aria-label=\"Footnote 3\"><sup class=\"footnote\">[3]<\/sup><\/a>,<a class=\"footnote\" title=\"Frandsen, G., &amp; Pennington, S. (2018). Abrams\u2019 clinical drug: Rationales for nursing practice\u00a0(11th ed.). Wolters Kluwer.\" id=\"return-footnote-213-4\" href=\"#footnote-213-4\" aria-label=\"Footnote 4\"><sup class=\"footnote\">[4]<\/sup><\/a>,<a class=\"footnote\" title=\"This work is a derivative of\u00a0DailyMed\u00a0by\u00a0U.S. National Library of Medicine in the Public Domain.\" id=\"return-footnote-213-5\" href=\"#footnote-213-5\" aria-label=\"Footnote 5\"><sup class=\"footnote\">[5]<\/sup><\/a><\/sup><\/p>\n<p>Table 5.9 Guaifenesin Medication Grid<\/p>\n<table class=\"grid\">\n<tbody>\n<tr>\n<th class=\"shaded\" style=\"width: 132.063px\" scope=\"col\">\n<h5><strong>Class\/Subclass<\/strong><\/h5>\n<\/th>\n<th class=\"shaded\" style=\"width: 165.063px\" scope=\"col\">\n<h5><strong>Prototype\/Generic<\/strong><\/h5>\n<\/th>\n<th class=\"shaded\" style=\"width: 382.063px\" scope=\"col\">\n<h5><strong>Nursing Considerations<\/strong><\/h5>\n<\/th>\n<th class=\"shaded\" style=\"width: 369.063px\" scope=\"col\">\n<h5><strong>Therapeutic Effects<\/strong><\/h5>\n<\/th>\n<th class=\"shaded\" style=\"width: 252.063px\" scope=\"col\">\n<h5><strong>Side\/Adverse Effects<\/strong><\/h5>\n<\/th>\n<\/tr>\n<tr>\n<th style=\"width: 132.063px\" scope=\"row\">Expectorant<\/th>\n<td style=\"width: 165.063px\"><a class=\"arrow\" href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=259c8b69-c625-4146-b888-34ef43b8385f\" target=\"_blank\" rel=\"noopener noreferrer\">guaifenesin<\/a><\/td>\n<td style=\"width: 382.063px\">No eating or drinking for 30 minutes after syrup<\/p>\n<p>Encourage client to cough and deep breathe<\/p>\n<p>Encourage increased fluid intake to thin secretions, if not contraindicated<\/td>\n<td style=\"width: 369.063px\">Helps loosen sputum (mucus) and thin bronchial secretions to make coughs more productive<\/td>\n<td style=\"width: 252.063px\">Increased drowsiness in large doses<\/p>\n<p>Gastrointestinal: Nausea, vomiting, and diarrhea<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<hr class=\"before-footnotes clear\" \/><div class=\"footnotes\"><ol><li id=\"footnote-213-1\">Frandsen, G., &amp; Pennington, S. (2018). <em>Abrams\u2019 clinical drug: Rationales for nursing practice <\/em>(11th ed.). Wolters Kluwer. <a href=\"#return-footnote-213-1\" class=\"return-footnote\" aria-label=\"Return to footnote 1\">&crarr;<\/a><\/li><li id=\"footnote-213-2\">uCentral from Unbound Medicine. <a href=\"https:\/\/www.unboundmedicine.com\/ucentral\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.unboundmedicine.com\/ucentral<\/a> <a href=\"#return-footnote-213-2\" class=\"return-footnote\" aria-label=\"Return to footnote 2\">&crarr;<\/a><\/li><li id=\"footnote-213-3\">This work is a derivative of\u00a0<a href=\"https:\/\/www.oercommons.org\/authoring\/54330-pharmacology-notes-nursing-implications-for-clinic\/view\" target=\"_blank\" rel=\"noopener noreferrer\">Pharmacology Notes: Nursing Implications for Clinical Practice<\/a>\u00a0by\u00a0<a href=\"https:\/\/www.oercommons.org\/profile\/213497\" target=\"_blank\" rel=\"noopener noreferrer\">Gloria Velarde<\/a>\u00a0licensed under\u00a0<a href=\"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">CC BY-NC-SA 4.0<\/a> <a href=\"#return-footnote-213-3\" class=\"return-footnote\" aria-label=\"Return to footnote 3\">&crarr;<\/a><\/li><li id=\"footnote-213-4\">Frandsen, G., &amp; Pennington, S. (2018). <em>Abrams\u2019 clinical drug: Rationales for nursing practice\u00a0<\/em>(11th ed.). Wolters Kluwer. <a href=\"#return-footnote-213-4\" class=\"return-footnote\" aria-label=\"Return to footnote 4\">&crarr;<\/a><\/li><li id=\"footnote-213-5\">This work is a derivative of\u00a0<a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/\" target=\"_blank\" rel=\"noopener noreferrer\">DailyMed<\/a>\u00a0by\u00a0<a href=\"https:\/\/www.nlm.nih.gov\/\" target=\"_blank\" rel=\"noopener noreferrer\">U.S. National Library of Medicine<\/a> in the <a href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/\" target=\"_blank\" rel=\"noopener noreferrer\">Public Domain<\/a>.  <a href=\"#return-footnote-213-5\" class=\"return-footnote\" aria-label=\"Return to footnote 5\">&crarr;<\/a><\/li><\/ol><\/div>","protected":false},"author":83,"menu_order":9,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[48],"contributor":[],"license":[],"class_list":["post-213","chapter","type-chapter","status-publish","hentry","chapter-type-numberless"],"part":186,"_links":{"self":[{"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/213","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/wp\/v2\/users\/83"}],"version-history":[{"count":1,"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/213\/revisions"}],"predecessor-version":[{"id":214,"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/213\/revisions\/214"}],"part":[{"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/parts\/186"}],"metadata":[{"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/213\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/wp\/v2\/media?parent=213"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/pressbooks\/v2\/chapter-type?post=213"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/wp\/v2\/contributor?post=213"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.ccconline.org\/accnursingpharmacology\/wp-json\/wp\/v2\/license?post=213"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}