{"id":4380,"date":"2019-06-17T18:10:31","date_gmt":"2019-06-17T18:10:31","guid":{"rendered":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/chapter\/3-9-energy-in-chemical-reactions-3\/"},"modified":"2023-11-30T17:50:58","modified_gmt":"2023-11-30T17:50:58","slug":"3-9-energy-in-chemical-reactions-3","status":"publish","type":"chapter","link":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/chapter\/3-9-energy-in-chemical-reactions-3\/","title":{"raw":"3.9\u00a0Energy in Chemical Reactions","rendered":"3.9\u00a0Energy in Chemical Reactions"},"content":{"raw":"&nbsp;\r\n<h1>Slow Burn<\/h1>\r\n[caption id=\"attachment_983\" align=\"alignright\" width=\"397\"]<img class=\" wp-image-983\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2019\/06\/Rusty-truck-2-scaled.jpg\" alt=\"Image shows a very rusty Ford truck with a surfboard in the back.\" width=\"397\" height=\"265\" \/> <em>Figure 3.9.1 Rusting is a type of combustion reaction.<\/em>[\/caption]\r\n\r\nThis old truck gives off a small amount of\u00a0heat\u00a0as it rusts. The rusting of iron is a chemical process. It occurs when iron and oxygen go through a\u00a0[pb_glossary id=\"5729\"]chemical reaction[\/pb_glossary]\u00a0similar to burning, or combustion. Obviously, the chemical reaction that occurs when something burns gives off\u00a0[pb_glossary id=\"5753\"]energy[\/pb_glossary]. You can feel the heat, and you may be able to see the light of flames. The rusting of iron is a much slower process, but it still gives off energy. It's just that it releases energy so slowly that you can't detect a change in\u00a0temperature.\r\n<div>\r\n<h1>The Role of\u00a0Energy in Chemical Reactions<\/h1>\r\n<\/div>\r\nMatter rusting or burning are common examples of chemical changes.\u00a0<strong>Chemical changes<\/strong>\u00a0involve\u00a0chemical reactions, in which some substances, called reactants, change at the molecular level to form new substances, which are called products. All chemical reactions involve\u00a0energy, but not all chemical reactions\u00a0<em>release<\/em>\u00a0energy,\u00a0like rusting and burning. In some chemical reactions, energy is\u00a0<em>absorbed<\/em>\u00a0rather than released.\r\n<h2>Exothermic Reactions<\/h2>\r\n[caption id=\"attachment_985\" align=\"alignleft\" width=\"400\"]<img class=\" wp-image-985\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/Compost-2.jpg\" alt=\"A large pile of compost in a field. The compost has a cloud of steam around it, indicating release of heat into the environment as a result of the decomposition process.\" width=\"400\" height=\"300\" \/> <em>Figure 3.9.2 Exothermic reactions release energy.<\/em>[\/caption]\r\n\r\nA\u00a0chemical reaction\u00a0that releases energy is called an\u00a0[pb_glossary id=\"5513\"]<strong>exothermic reaction<\/strong>[\/pb_glossary]. This type of reaction can be represented\u00a0with this\u00a0general chemical equation:\r\n\r\nReactants \u2192 Products +\u00a0<span style=\"color: #ff0000;\"><strong>Heat<\/strong><\/span>\r\n\r\nAnother example of an exothermic reaction is chlorine combining with sodium to form table salt. The decomposition of organic matter also releases energy because of exothermic reactions. Sometimes on a chilly morning, you can see steam rising from a compost pile because of these chemical reactions (see photo in Figure 3.9.2).\r\n<div>\r\n\r\nThis compost pile is steaming because it is much warmer than the chilly air around it. The heat comes from all the exothermic chemical reactions taking place inside the compost as it decomposes.\r\n\r\n<\/div>\r\nA special type of exothermic reaction is an [pb_glossary id=\"993\"]<strong>exergonic reaction<\/strong>[\/pb_glossary]- not only do exergonic reactions release energy, but in addition, they occur spontaneously.\u00a0 Many cell processes rely on exergonic reactions: in a chemical process\u00a0called\u00a0cellular respiration, which is\u00a0similar to combustion, the sugar glucose is \"burned\" to provide\u00a0cells\u00a0with energy.\r\n<h2>Endothermic Reactions<\/h2>\r\nA\u00a0chemical reaction\u00a0that absorbs [pb_glossary id=\"5753\"]energy[\/pb_glossary] is called an\u00a0<strong>[pb_glossary id=\"5517\"]endothermic reaction[\/pb_glossary]<\/strong>. This type of reaction can also be represented by a general chemical equation:\r\n\r\nReactants +<strong><span style=\"color: #ff0000;\">\u00a0Energy<\/span><\/strong>\u00a0\u2192 Products\r\n\r\n[caption id=\"attachment_998\" align=\"alignright\" width=\"334\"]<img class=\"wp-image-998\" style=\"font-size: 1em;\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/Cold-Pack-2.png\" alt=\"Image shows a graphic of an instant cold pack. There are instructions for use on the front of the package. These instructions indicate that to use the cold pack, one must squeeze the package, mix the contents by kneading the bag. Once the cold pack is activated, it can be use to apply cold to minor injuries. The image also lists the two compounds in a cold pack: ammonium nitrate and water. Before use, these two compounds are kept separate, but once the cold pack is activated, these two compounds mix, producing an endothermic reaction, producing &quot;cold&quot;.\" width=\"334\" height=\"274\" \/> <em>Figure 3.9.3 This pack gets cold because of an endothermic reaction.<\/em>[\/caption]\r\n\r\nDid you ever use a chemical cold pack like the one pictured? The pack cools down because of an\u00a0endothermic reaction. When a tube inside the pack is broken, it releases ammonium nitrate, a chemical that reacts with\u00a0water inside the pack. This reaction absorbs heat energy and quickly cools down the contents of the pack.\r\n\r\nMany other chemical processes involve endothermic reactions. Most cooking and baking, for example, involves the use of energy to produce chemical reactions. You can't bake a cake or cook an egg without adding heat energy.\r\n\r\nArguably, the most important endothermic reactions occur during\u00a0photosynthesis. When plants produce sugar by photosynthesis, they take in light energy to power the necessary endothermic reactions. The sugar they produce provides plants and virtually all other living things with glucose for\u00a0cellular respiration.\r\n<div>\r\n<h2>Activation Energy<\/h2>\r\n<\/div>\r\nAll chemical reactions\u00a0require\u00a0energy to get started. Even reactions that release energy need a boost of energy in order to begin. The energy needed to start a chemical reaction is called\u00a0<strong>[pb_glossary id=\"5519\"]activation energy[\/pb_glossary]<\/strong>. Activation energy is like the push a child needs to start going down a playground slide. The push gives the child enough energy to start moving, but once she starts, she keeps moving without being pushed again. Activation energy is illustrated in the graph in Figure 3.9.4.\r\n\r\n[caption id=\"attachment_1004\" align=\"aligncenter\" width=\"338\"]<img class=\"wp-image-1004\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/Activation-energy-2.png\" alt=\"Image shows a graph of the energy change during a chemical reaction. The reactants have a higher energy level than the products, implying that the reaction is exothermic. However, the reaction cannot occur spontaneously, it requires a small input of energy to get started. This input of energy is the activation energy.\" width=\"338\" height=\"351\" \/> <em>Figure 3.9.4 Even though this reaction is exothermic, it requires \"help\" to get started. This \"help\" is the activation energy.<\/em>[\/caption]\r\n\r\nWhy do chemical reactions need energy to get started? In order for reactions to begin, reactant molecules must bump into each other, so they must be moving \u2014 and movement requires energy. When reactant molecules bump together, they may repel each other because of intermolecular forces pushing them apart. Energy is also required to overcome these forces so the molecules can come together and react.\r\n<div>\r\n<div class=\"textbox textbox--key-takeaways\"><header class=\"textbox__header\">\r\n<h1 class=\"textbox__title\"><span style=\"color: #ffffff;\">3.9 Summary<\/span><\/h1>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n<ul>\r\n \t<li>All [pb_glossary id=\"5729\"]chemical reactions[\/pb_glossary] involve [pb_glossary id=\"5753\"]energy[\/pb_glossary]. [pb_glossary id=\"5547\"]Exothermic reactions[\/pb_glossary] release energy. [pb_glossary id=\"1009\"]Endothermic reactions[\/pb_glossary] absorb energy.<\/li>\r\n \t<li>All chemical reactions need [pb_glossary id=\"5519\"]activation energy[\/pb_glossary] to begin. Activation energy provides the \"push\" needed to get the reaction started.<\/li>\r\n<\/ul>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<div>\r\n<div class=\"textbox textbox--exercises\"><header class=\"textbox__header\">\r\n<h1 class=\"textbox__title\"><span style=\"color: #ffffff;\">3.9 Review Questions<\/span><\/h1>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n<ol>\r\n \t<li>Compare\u00a0endothermic and exothermic chemical reactions. Give an example of a process that involves each type of reaction.<\/li>\r\n \t<li>Define activation energy.<\/li>\r\n \t<li>Explain why chemical reactions require activation energy.<\/li>\r\n \t<li>Heat is a form of ____________ .<\/li>\r\n \t<li>In which type of reaction is heat added to the reactants?<\/li>\r\n \t<li>In which type of reaction is heat produced?<\/li>\r\n \t<li>If there was no energy added to an endothermic reaction, would that reaction occur? Why or why not?<\/li>\r\n \t<li>If there was no energy added to an exothermic reaction, would that reaction occur? Why or why not?<\/li>\r\n \t<li>Explain why a chemical cold pack feels cold when activated.<\/li>\r\n \t<li>Explain why cellular respiration and photosynthesis are \u201copposites\u201d of each other.<\/li>\r\n \t<li>Explain how the sun gives our\u00a0cells\u00a0energy indirectly.<\/li>\r\n<\/ol>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<div class=\"textbox textbox--examples\"><header class=\"textbox__header\">\r\n<h1 class=\"textbox__title\"><span style=\"color: #ffffff;\">3.9 Explore More<\/span><\/h1>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n\r\nhttps:\/\/www.youtube.com\/watch?time_continue=1&amp;v=D0ZyjpAin_Y&amp;feature=emb_logo\r\n<p style=\"text-align: center;\">Activation energy: Kickstarting chemical reactions - Vance Kite, TED-Ed, 2013.<\/p>\r\nhttps:\/\/www.youtube.com\/watch?time_continue=3&amp;v=znsPa1BSaIM&amp;feature=emb_logo\r\n<p style=\"text-align: center;\">The Sci Guys: Science at Home - SE1 - EP7: Hot Ice - Exothermic Reactions and Supercooled solutions, The Sci Guys, 2013<\/p>\r\n\r\n<\/div>\r\n<\/div>\r\n<h2>Attributions<\/h2>\r\n<strong>Figure 3.9.1<\/strong>\r\n\r\n<a href=\"https:\/\/unsplash.com\/photos\/YKQawNUINXA\" rel=\"cc:attributionURL\">Rusty truck<\/a> by\u00a0<a href=\"https:\/\/unsplash.com\/@ross_sokolovski?utm_source=unsplash&amp;utm_medium=referral&amp;utm_content=creditCopyText\" rel=\"dc:creator\">Ross Sokolovski<\/a> on <a href=\"https:\/\/unsplash.com\/\">Unsplash<\/a> is used under the <a class=\"ICezk _2GAZm _2WvKc\" href=\"https:\/\/unsplash.com\/license\">Unsplash License<\/a> (https:\/\/unsplash.com\/license).\r\n\r\n<strong>Figure 3.9.2<\/strong>\r\n\r\n<a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Gently_steaming_compost%5E_-_geograph.org.uk_-_79035.jpg\" rel=\"cc:attributionURL\">Compost<\/a>\/\u00a0<i>Gently steaming compost!<\/i> by <a href=\"https:\/\/www.geograph.org.uk\/profile\/759\">John Winfield<\/a>\u00a0on Wikimedia Commons, is used under a\u00a0<span style=\"text-align: initial; font-size: 1em;\"><span class=\"plainlinks noprint\"><a class=\"external text\" href=\"https:\/\/creativecommons.org\/licenses\/by-sa\/2.0\/\" rel=\"nofollow\">CC BY-SA 2.0<\/a> (https:\/\/creativecommons.org\/licenses\/by-sa\/2.0\/) license.<\/span><\/span>\r\n\r\n<strong>Figure 3.9.3<\/strong>\r\n\r\n<a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:CNX_Chem_11_01_Icepack.png\" rel=\"cc:attributionURL\">Cold Pack<\/a> by <a href=\"https:\/\/cnx.org\/contents\/havxkyvS@12.2:B6X9tZ1p@15\/Energy-Basics\">OpenStax \/CNX<\/a> on Wikimedia Commons, is used under a <a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.en\">CC BY 4.0<\/a> (https:\/\/creativecommons.org\/licenses\/by\/4.0) license.\r\n\r\n<strong>Figure 3.9.4\u00a0<\/strong>\r\n\r\n<a href=\"https:\/\/www.ck12.org\/book\/CK-12-College-Human-Biology\/section\/3.8\/\" rel=\"cc:attributionURL\">Activation energy<\/a>\u00a0by\u00a0<a href=\"https:\/\/www.ck12.org\/book\/CK-12-College-Human-Biology\/section\/3.8\/\" rel=\"dc:creator\">CK12<\/a> is used under a <a href=\"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/\">CC BY-NC 3.0<\/a> (https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/) license.\r\n\r\n<span style=\"font-size: 1.424em; font-weight: bold;\">References<\/span>\r\n<p class=\"hanging-indent\"><span style=\"font-size: 1em;\">Brainard, J., Henderson, R. \/ <\/span><span style=\"text-align: initial; font-size: 1em;\">CK12. <\/span><span style=\"font-size: 1em;\">(2018, August 22). Figure: Activation Energy [digital image]. In <\/span><em style=\"font-size: 1em;\">CK-12 College Human Biology<\/em><span style=\"font-size: 1em;\">. CK12. https:\/\/flexbooks.ck12.org\/cbook\/ck-12-college-human-biology-flexbook-2.0<\/span><\/p>\r\n<p class=\"hanging-indent\"><span class=\"name\" style=\"text-align: initial; font-size: 1em;\">OpenStax. (2019, <\/span><span style=\"text-align: initial; font-size: 1em;\">Jul 30)<\/span><span style=\"text-align: initial; font-size: 1em;\">, Figure 6(b) A\u00a0<mtext class=\"q-match\">cold<\/mtext>\u00a0<mtext class=\"q-match\">pack<\/mtext>\u00a0uses an endothermic process to create the sensation of\u00a0<mtext class=\"q-match\">cold<\/mtext>. <em>OpenStax Chemistry.<\/em> OpenStax CNX. http:\/\/cnx.org\/contents\/85abf193-2bd2-4908-8563-90b8a7ac8df6@12.2. (Credit: a modification of\u00a0 work by \u201cSkatebiker\u201d\/Wikimedia commons).<\/span><\/p>\r\n<p class=\"hanging-indent\">TED-Ed. (2013, January 9). Activation energy: Kickstarting chemical reactions - Vance Kite. YouTube. https:\/\/www.youtube.com\/watch?v=D0ZyjpAin_Y&amp;feature=youtu.be<\/p>\r\n<p class=\"hanging-indent\">The Sci Guys. (2013, April 4). The Sci Guys: Science at home - SE1 - EP7: Hot ice - Exothermic reactions and supercooled solutions. YouTube. https:\/\/www.youtube.com\/watch?v=znsPa1BSaIM&amp;feature=youtu.be<\/p>\r\n&nbsp;","rendered":"<p>&nbsp;<\/p>\n<h1>Slow Burn<\/h1>\n<figure id=\"attachment_983\" aria-describedby=\"caption-attachment-983\" style=\"width: 397px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-983\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2019\/06\/Rusty-truck-2-scaled.jpg\" alt=\"Image shows a very rusty Ford truck with a surfboard in the back.\" width=\"397\" height=\"265\" \/><figcaption id=\"caption-attachment-983\" class=\"wp-caption-text\"><em>Figure 3.9.1 Rusting is a type of combustion reaction.<\/em><\/figcaption><\/figure>\n<p>This old truck gives off a small amount of\u00a0heat\u00a0as it rusts. The rusting of iron is a chemical process. It occurs when iron and oxygen go through a\u00a0<a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_5729\">chemical reaction<\/a>\u00a0similar to burning, or combustion. Obviously, the chemical reaction that occurs when something burns gives off\u00a0<a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_5753\">energy<\/a>. You can feel the heat, and you may be able to see the light of flames. The rusting of iron is a much slower process, but it still gives off energy. It&#8217;s just that it releases energy so slowly that you can&#8217;t detect a change in\u00a0temperature.<\/p>\n<div>\n<h1>The Role of\u00a0Energy in Chemical Reactions<\/h1>\n<\/div>\n<p>Matter rusting or burning are common examples of chemical changes.\u00a0<strong>Chemical changes<\/strong>\u00a0involve\u00a0chemical reactions, in which some substances, called reactants, change at the molecular level to form new substances, which are called products. All chemical reactions involve\u00a0energy, but not all chemical reactions\u00a0<em>release<\/em>\u00a0energy,\u00a0like rusting and burning. In some chemical reactions, energy is\u00a0<em>absorbed<\/em>\u00a0rather than released.<\/p>\n<h2>Exothermic Reactions<\/h2>\n<figure id=\"attachment_985\" aria-describedby=\"caption-attachment-985\" style=\"width: 400px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-985\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/Compost-2.jpg\" alt=\"A large pile of compost in a field. The compost has a cloud of steam around it, indicating release of heat into the environment as a result of the decomposition process.\" width=\"400\" height=\"300\" \/><figcaption id=\"caption-attachment-985\" class=\"wp-caption-text\"><em>Figure 3.9.2 Exothermic reactions release energy.<\/em><\/figcaption><\/figure>\n<p>A\u00a0chemical reaction\u00a0that releases energy is called an\u00a0<a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_5513\"><strong>exothermic reaction<\/strong><\/a>. This type of reaction can be represented\u00a0with this\u00a0general chemical equation:<\/p>\n<p>Reactants \u2192 Products +\u00a0<span style=\"color: #ff0000;\"><strong>Heat<\/strong><\/span><\/p>\n<p>Another example of an exothermic reaction is chlorine combining with sodium to form table salt. The decomposition of organic matter also releases energy because of exothermic reactions. Sometimes on a chilly morning, you can see steam rising from a compost pile because of these chemical reactions (see photo in Figure 3.9.2).<\/p>\n<div>\n<p>This compost pile is steaming because it is much warmer than the chilly air around it. The heat comes from all the exothermic chemical reactions taking place inside the compost as it decomposes.<\/p>\n<\/div>\n<p>A special type of exothermic reaction is an <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_993\"><strong>exergonic reaction<\/strong><\/a>&#8211; not only do exergonic reactions release energy, but in addition, they occur spontaneously.\u00a0 Many cell processes rely on exergonic reactions: in a chemical process\u00a0called\u00a0cellular respiration, which is\u00a0similar to combustion, the sugar glucose is &#8220;burned&#8221; to provide\u00a0cells\u00a0with energy.<\/p>\n<h2>Endothermic Reactions<\/h2>\n<p>A\u00a0chemical reaction\u00a0that absorbs <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_5753\">energy<\/a> is called an\u00a0<strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_5517\">endothermic reaction<\/a><\/strong>. This type of reaction can also be represented by a general chemical equation:<\/p>\n<p>Reactants +<strong><span style=\"color: #ff0000;\">\u00a0Energy<\/span><\/strong>\u00a0\u2192 Products<\/p>\n<figure id=\"attachment_998\" aria-describedby=\"caption-attachment-998\" style=\"width: 334px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-998\" style=\"font-size: 1em;\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/Cold-Pack-2.png\" alt=\"Image shows a graphic of an instant cold pack. There are instructions for use on the front of the package. These instructions indicate that to use the cold pack, one must squeeze the package, mix the contents by kneading the bag. Once the cold pack is activated, it can be use to apply cold to minor injuries. The image also lists the two compounds in a cold pack: ammonium nitrate and water. Before use, these two compounds are kept separate, but once the cold pack is activated, these two compounds mix, producing an endothermic reaction, producing &quot;cold&quot;.\" width=\"334\" height=\"274\" \/><figcaption id=\"caption-attachment-998\" class=\"wp-caption-text\"><em>Figure 3.9.3 This pack gets cold because of an endothermic reaction.<\/em><\/figcaption><\/figure>\n<p>Did you ever use a chemical cold pack like the one pictured? The pack cools down because of an\u00a0endothermic reaction. When a tube inside the pack is broken, it releases ammonium nitrate, a chemical that reacts with\u00a0water inside the pack. This reaction absorbs heat energy and quickly cools down the contents of the pack.<\/p>\n<p>Many other chemical processes involve endothermic reactions. Most cooking and baking, for example, involves the use of energy to produce chemical reactions. You can&#8217;t bake a cake or cook an egg without adding heat energy.<\/p>\n<p>Arguably, the most important endothermic reactions occur during\u00a0photosynthesis. When plants produce sugar by photosynthesis, they take in light energy to power the necessary endothermic reactions. The sugar they produce provides plants and virtually all other living things with glucose for\u00a0cellular respiration.<\/p>\n<div>\n<h2>Activation Energy<\/h2>\n<\/div>\n<p>All chemical reactions\u00a0require\u00a0energy to get started. Even reactions that release energy need a boost of energy in order to begin. The energy needed to start a chemical reaction is called\u00a0<strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_5519\">activation energy<\/a><\/strong>. Activation energy is like the push a child needs to start going down a playground slide. The push gives the child enough energy to start moving, but once she starts, she keeps moving without being pushed again. Activation energy is illustrated in the graph in Figure 3.9.4.<\/p>\n<figure id=\"attachment_1004\" aria-describedby=\"caption-attachment-1004\" style=\"width: 338px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1004\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/Activation-energy-2.png\" alt=\"Image shows a graph of the energy change during a chemical reaction. The reactants have a higher energy level than the products, implying that the reaction is exothermic. However, the reaction cannot occur spontaneously, it requires a small input of energy to get started. This input of energy is the activation energy.\" width=\"338\" height=\"351\" \/><figcaption id=\"caption-attachment-1004\" class=\"wp-caption-text\"><em>Figure 3.9.4 Even though this reaction is exothermic, it requires &#8220;help&#8221; to get started. This &#8220;help&#8221; is the activation energy.<\/em><\/figcaption><\/figure>\n<p>Why do chemical reactions need energy to get started? In order for reactions to begin, reactant molecules must bump into each other, so they must be moving \u2014 and movement requires energy. When reactant molecules bump together, they may repel each other because of intermolecular forces pushing them apart. Energy is also required to overcome these forces so the molecules can come together and react.<\/p>\n<div>\n<div class=\"textbox textbox--key-takeaways\">\n<header class=\"textbox__header\">\n<h1 class=\"textbox__title\"><span style=\"color: #ffffff;\">3.9 Summary<\/span><\/h1>\n<\/header>\n<div class=\"textbox__content\">\n<ul>\n<li>All <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_5729\">chemical reactions<\/a> involve <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_5753\">energy<\/a>. <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_5547\">Exothermic reactions<\/a> release energy. <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1009\">Endothermic reactions<\/a> absorb energy.<\/li>\n<li>All chemical reactions need <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_5519\">activation energy<\/a> to begin. Activation energy provides the &#8220;push&#8221; needed to get the reaction started.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<div class=\"textbox textbox--exercises\">\n<header class=\"textbox__header\">\n<h1 class=\"textbox__title\"><span style=\"color: #ffffff;\">3.9 Review Questions<\/span><\/h1>\n<\/header>\n<div class=\"textbox__content\">\n<ol>\n<li>Compare\u00a0endothermic and exothermic chemical reactions. Give an example of a process that involves each type of reaction.<\/li>\n<li>Define activation energy.<\/li>\n<li>Explain why chemical reactions require activation energy.<\/li>\n<li>Heat is a form of ____________ .<\/li>\n<li>In which type of reaction is heat added to the reactants?<\/li>\n<li>In which type of reaction is heat produced?<\/li>\n<li>If there was no energy added to an endothermic reaction, would that reaction occur? Why or why not?<\/li>\n<li>If there was no energy added to an exothermic reaction, would that reaction occur? Why or why not?<\/li>\n<li>Explain why a chemical cold pack feels cold when activated.<\/li>\n<li>Explain why cellular respiration and photosynthesis are \u201copposites\u201d of each other.<\/li>\n<li>Explain how the sun gives our\u00a0cells\u00a0energy indirectly.<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"textbox textbox--examples\">\n<header class=\"textbox__header\">\n<h1 class=\"textbox__title\"><span style=\"color: #ffffff;\">3.9 Explore More<\/span><\/h1>\n<\/header>\n<div class=\"textbox__content\">\n<p><iframe loading=\"lazy\" id=\"oembed-1\" title=\"Activation energy: Kickstarting chemical reactions - Vance Kite\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/D0ZyjpAin_Y?start=1&#38;feature=oembed\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p style=\"text-align: center;\">Activation energy: Kickstarting chemical reactions &#8211; Vance Kite, TED-Ed, 2013.<\/p>\n<p><iframe loading=\"lazy\" id=\"oembed-2\" title=\"The Sci Guys: Science at Home - SE1 - EP7: Hot Ice - Exothermic Reactions and Supercooled solutions\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/znsPa1BSaIM?start=3&#38;feature=oembed\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p style=\"text-align: center;\">The Sci Guys: Science at Home &#8211; SE1 &#8211; EP7: Hot Ice &#8211; Exothermic Reactions and Supercooled solutions, The Sci Guys, 2013<\/p>\n<\/div>\n<\/div>\n<h2>Attributions<\/h2>\n<p><strong>Figure 3.9.1<\/strong><\/p>\n<p><a href=\"https:\/\/unsplash.com\/photos\/YKQawNUINXA\" rel=\"cc:attributionURL\">Rusty truck<\/a> by\u00a0<a href=\"https:\/\/unsplash.com\/@ross_sokolovski?utm_source=unsplash&amp;utm_medium=referral&amp;utm_content=creditCopyText\" rel=\"dc:creator\">Ross Sokolovski<\/a> on <a href=\"https:\/\/unsplash.com\/\">Unsplash<\/a> is used under the <a class=\"ICezk _2GAZm _2WvKc\" href=\"https:\/\/unsplash.com\/license\">Unsplash License<\/a> (https:\/\/unsplash.com\/license).<\/p>\n<p><strong>Figure 3.9.2<\/strong><\/p>\n<p><a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Gently_steaming_compost%5E_-_geograph.org.uk_-_79035.jpg\" rel=\"cc:attributionURL\">Compost<\/a>\/\u00a0<i>Gently steaming compost!<\/i> by <a href=\"https:\/\/www.geograph.org.uk\/profile\/759\">John Winfield<\/a>\u00a0on Wikimedia Commons, is used under a\u00a0<span style=\"text-align: initial; font-size: 1em;\"><span class=\"plainlinks noprint\"><a class=\"external text\" href=\"https:\/\/creativecommons.org\/licenses\/by-sa\/2.0\/\" rel=\"nofollow\">CC BY-SA 2.0<\/a> (https:\/\/creativecommons.org\/licenses\/by-sa\/2.0\/) license.<\/span><\/span><\/p>\n<p><strong>Figure 3.9.3<\/strong><\/p>\n<p><a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:CNX_Chem_11_01_Icepack.png\" rel=\"cc:attributionURL\">Cold Pack<\/a> by <a href=\"https:\/\/cnx.org\/contents\/havxkyvS@12.2:B6X9tZ1p@15\/Energy-Basics\">OpenStax \/CNX<\/a> on Wikimedia Commons, is used under a <a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.en\">CC BY 4.0<\/a> (https:\/\/creativecommons.org\/licenses\/by\/4.0) license.<\/p>\n<p><strong>Figure 3.9.4\u00a0<\/strong><\/p>\n<p><a href=\"https:\/\/www.ck12.org\/book\/CK-12-College-Human-Biology\/section\/3.8\/\" rel=\"cc:attributionURL\">Activation energy<\/a>\u00a0by\u00a0<a href=\"https:\/\/www.ck12.org\/book\/CK-12-College-Human-Biology\/section\/3.8\/\" rel=\"dc:creator\">CK12<\/a> is used under a <a href=\"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/\">CC BY-NC 3.0<\/a> (https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/) license.<\/p>\n<p><span style=\"font-size: 1.424em; font-weight: bold;\">References<\/span><\/p>\n<p class=\"hanging-indent\"><span style=\"font-size: 1em;\">Brainard, J., Henderson, R. \/ <\/span><span style=\"text-align: initial; font-size: 1em;\">CK12. <\/span><span style=\"font-size: 1em;\">(2018, August 22). Figure: Activation Energy [digital image]. In <\/span><em style=\"font-size: 1em;\">CK-12 College Human Biology<\/em><span style=\"font-size: 1em;\">. CK12. https:\/\/flexbooks.ck12.org\/cbook\/ck-12-college-human-biology-flexbook-2.0<\/span><\/p>\n<p class=\"hanging-indent\"><span class=\"name\" style=\"text-align: initial; font-size: 1em;\">OpenStax. (2019, <\/span><span style=\"text-align: initial; font-size: 1em;\">Jul 30)<\/span><span style=\"text-align: initial; font-size: 1em;\">, Figure 6(b) A\u00a0cold\u00a0pack\u00a0uses an endothermic process to create the sensation of\u00a0cold. <em>OpenStax Chemistry.<\/em> OpenStax CNX. http:\/\/cnx.org\/contents\/85abf193-2bd2-4908-8563-90b8a7ac8df6@12.2. (Credit: a modification of\u00a0 work by \u201cSkatebiker\u201d\/Wikimedia commons).<\/span><\/p>\n<p class=\"hanging-indent\">TED-Ed. (2013, January 9). Activation energy: Kickstarting chemical reactions &#8211; Vance Kite. YouTube. https:\/\/www.youtube.com\/watch?v=D0ZyjpAin_Y&amp;feature=youtu.be<\/p>\n<p class=\"hanging-indent\">The Sci Guys. (2013, April 4). The Sci Guys: Science at home &#8211; SE1 &#8211; EP7: Hot ice &#8211; Exothermic reactions and supercooled solutions. YouTube. https:\/\/www.youtube.com\/watch?v=znsPa1BSaIM&amp;feature=youtu.be<\/p>\n<p>&nbsp;<\/p>\n<div class=\"glossary\"><span class=\"screen-reader-text\" id=\"definition\">definition<\/span><template id=\"term_4380_5729\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_4380_5729\"><div tabindex=\"-1\"><p>A chemical reaction is a process that leads to the chemical transformation of one set of chemical substances to another.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_4380_5753\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_4380_5753\"><div tabindex=\"-1\"><p>The ability to do work.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_4380_5513\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_4380_5513\"><div tabindex=\"-1\"><p>A chemical reaction that releases energy through light or heat.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_4380_993\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_4380_993\"><div tabindex=\"-1\"><p>Created by:\u00a0CK-12\/Adapted by Christine Miller<\/p>\n<figure id=\"attachment_1795\" aria-describedby=\"caption-attachment-1795\" style=\"width: 333px\" class=\"wp-caption aligncenter\"><img class=\"wp-image-1795\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2019\/06\/SMores-1-scaled.jpg\" alt=\"Image shows a photo of the ingredients for smores sitting on a table. In the background, a campfire is burning.\" width=\"333\" height=\"500\"><figcaption id=\"caption-attachment-1795\" class=\"wp-caption-text\"><em>Figure 4.10.1 Ready to make s'mores!<\/em><\/figcaption><\/figure>\n<div>\n<h1>Bring on the S'mores!<\/h1>\n<\/div>\n<p>This inviting camp fire can be used for both\u00a0heat\u00a0and light. Heat and light are two\u00a0forms of <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_302\">energy<\/a>\u00a0that are released when a fuel like wood is burned. The\u00a0<a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_175\">cells\u00a0<\/a>of living things also get\u00a0energy\u00a0by \"burning.\" They \"burn\" <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_317\">glucose<\/a> in\u00a0a\u00a0process called<a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1172\"> cellular respiration<\/a>.<\/p>\n<div>\n<h1>What Is Cellular Respiration?<\/h1>\n<\/div>\n<p><strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1172\">Cellular respiration<\/a><\/strong>\u00a0is the process by which living\u00a0cells\u00a0break down <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_317\">glucose<\/a> molecules and release\u00a0<a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_302\">energy<\/a>. The process is similar to burning, although it doesn\u2019t produce light or intense\u00a0heat\u00a0as a campfire does. This is because cellular respiration releases the energy in glucose\u00a0<em>slowly\u00a0<\/em>and<em>\u00a0<\/em>in many small steps. It uses the\u00a0energy\u00a0released to form molecules of\u00a0<strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1623\">ATP<\/a><\/strong>, the energy-carrying molecules that\u00a0cells\u00a0use to power biochemical processes. In this way, cellular respiration is an example of energy coupling: glucose is broken down in an exothermic reaction, and then the energy from this reaction powers the endothermic reaction of the formation of ATP.\u00a0 Cellular respiration involves many\u00a0chemical reactions, but they can all be summed up with this chemical equation:<\/p>\n<p style=\"text-align: center\"><strong>C<sub>6<\/sub>H<sub>12<\/sub>O<sub>6<\/sub>\u00a0 6O<sub>2<\/sub>\u00a0\u2192 6CO<sub>2<\/sub>\u00a0 6H<sub>2<\/sub>O Chemical Energy (in ATP)<\/strong><\/p>\n<p>In words, the equation shows that glucose (C<sub>6<\/sub>H<sub>12<\/sub>O<sub>6<\/sub>)\u00a0and oxygen (O<sub>2<\/sub>)\u00a0react to form carbon dioxide (CO<sub>2<\/sub>) and\u00a0water\u00a0(H<sub>2<\/sub>O), releasing energy in the process. Because oxygen is required for cellular respiration, it is an\u00a0<a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1796\"><strong>aerobic<\/strong><\/a> process.<\/p>\n<p>Cellular respiration occurs in the <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_175\">cells<\/a> of all living things, both autotrophs and <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1716\">heterotrophs<\/a>. All of them burn <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_317\">glucose<\/a> to form <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1623\">ATP<\/a>. The reactions of <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1172\">cellular respiration<\/a> can be grouped into three stages: glycolysis, the Krebs cycle (also called the citric acid cycle), and electron transport. Figure 4.10.2 gives an overview of these three stages, which are also described in detail below.<\/p>\n<figure id=\"attachment_1797\" aria-describedby=\"caption-attachment-1797\" style=\"width: 720px\" class=\"wp-caption aligncenter\"><img class=\"wp-image-1797\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/Carbohydrate_Metabolism-1-scaled.jpg\" alt=\"Image shows a diagram of the four stages in cellular respiration: Glycolysis, transition reaction, Kreb's cycle, and the electron transport system.\" width=\"720\" height=\"1122\"><figcaption id=\"caption-attachment-1797\" class=\"wp-caption-text\"><em>Figure 4.10.2 Cellular respiration takes place in the stages shown here. The process begins with a molecule of glucose, which has six carbon atoms. What happens to each of these atoms of carbon?<\/em><\/figcaption><\/figure>\n<div>\n<p>&nbsp;<\/p>\n<\/div>\n<div>\n<h1>Cellular Respiration Stage I:\u00a0Glycolysis<\/h1>\n<\/div>\n<p>The first stage of cellular respiration is\u00a0<strong>glycolysis<\/strong>,\u00a0which happens\u00a0in the <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1608\">cytosol<\/a> of the <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1459\">cytoplasm<\/a>.<\/p>\n<h2>Splitting Glucose<\/h2>\n<p>The word\u00a0<em>glycolysis<\/em>\u00a0literally means \u201cglucose splitting,\u201d which is exactly what happens in this stage.\u00a0<a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_304\">Enzymes<\/a>\u00a0split a molecule of glucose into two molecules of pyruvate (also known as pyruvic acid). This occurs in several steps, as summarized in the\u00a0following\u00a0diagram.<\/p>\n<figure id=\"attachment_1800\" aria-describedby=\"caption-attachment-1800\" style=\"width: 784px\" class=\"wp-caption aligncenter\"><img class=\"wp-image-1800\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/Glycolysis-1.png\" alt=\"\" width=\"784\" height=\"523\"><figcaption id=\"caption-attachment-1800\" class=\"wp-caption-text\"><em>Figure 4.10.3 Glycolysis is a complex ten-step reaction that ultimately converts glucose into two molecules of pyruvate.\u00a0This releases energy, which is transferred to ATP. How many ATP molecules are made during this stage of cellular respiration?<\/em><\/figcaption><\/figure>\n<h2>Results of Glycolysis<\/h2>\n<p>Energy is needed at the start of glycolysis to split the glucose molecule into two pyruvate molecules which go on to stage II of cellular respiration. The energy needed to split glucose is provided by two molecules of ATP; this is called the energy investment phase. As glycolysis proceeds, energy is released, and the energy is used to make four molecules of ATP; this is the energy harvesting phase. As a result, there is a <em>net gain<\/em> of two ATP molecules during glycolysis. During this stage, high-energy electrons are also transferred to molecules of NAD \u00a0to produce two molecules of NADH, another energy-carrying molecule. NADH is used in stage III of cellular respiration to make more ATP.<\/p>\n<h2>Transition Reaction<\/h2>\n<p>Before pyruvate can enter the next stage of cellular respiration it needs to be modified slightly.\u00a0 The transition reaction is a very short reaction which converts the two molecules of pyruvate to two molecules of acetyl CoA, carbon dioxide, and two high energy electron pairs convert NAD to NADH.\u00a0 The carbon dioxide is released, the acetyl CoA moves to the mitochondria to enter the Kreb's Cycle (stage II), and the NADH carries the high energy electrons to the Electron Transport System (stage III).<\/p>\n<figure id=\"attachment_9093\" aria-describedby=\"caption-attachment-9093\" style=\"width: 747px\" class=\"wp-caption aligncenter\"><img class=\" wp-image-9093\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/Transition-Reaction-4-10-14-1.png\" alt=\"In the transition reaction, two molecules of pyruvate are converted to two molecules of acetyl coA and two molecules of carbon dioxide. The acetyl CoA moves to the Kreb's cycle, the carbon dioxide diffuses out of the cell, and two hydrogen atoms are carried on NADH to the ETS.\" width=\"747\" height=\"485\"><figcaption id=\"caption-attachment-9093\" class=\"wp-caption-text\"><em>Figure 4.10.14: During the Transition Reaction, pyruvate is converted to acetyl CoA and carbon dioxide.<\/em><\/figcaption><\/figure>\n<div>\n<h2>Structure of the Mitochondrion<\/h2>\n<\/div>\n<figure id=\"attachment_1804\" aria-describedby=\"caption-attachment-1804\" style=\"width: 496px\" class=\"wp-caption alignleft\"><img class=\"wp-image-1804\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/Mitochondrion-1.png\" alt=\"Image shows a diagram of a mitochondria. Several structures are labelled including cristae, matrix, DNA, intermembrane space, inner membrane, outer membrane, and ATP synthase particles.\" width=\"496\" height=\"341\"><figcaption id=\"caption-attachment-1804\" class=\"wp-caption-text\"><em>Figure 4.10.5 Labelled mitochondrion structure. <\/em><\/figcaption><\/figure>\n<p>Before you read about the last two stages of cellular respiration, you need to know more about the <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1579\">mitochondrion<\/a>, where these two stages take place. A diagram of a mitochondrion is shown in Figure 4.10.5.<\/p>\n<div>\n<p>The structure of a mitochondrion is defined by an inner and outer membrane. This structure plays an important role in aerobic respiration.<\/p>\n<\/div>\n<p>As you can see from the figure, a mitochondrion has an inner and outer membrane. The space between the inner and outer membrane is called the\u00a0<strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1811\">intermembrane space<\/a><\/strong>. The space enclosed by the inner membrane is called the\u00a0<strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1812\">matrix<\/a><\/strong>. The second stage of cellular respiration (the Krebs cycle) takes place in the matrix. The third stage (electron\u00a0transport)\u00a0happens on\u00a0the inner membrane.<\/p>\n<div>\n<h1>Cellular Respiration Stage II: The\u00a0Krebs Cycle<\/h1>\n<\/div>\n<p>Recall that glycolysis produces two molecules of pyruvate (pyruvic acid), which are then converted to acetyl CoA during the short transition reaction. These molecules enter the matrix of a mitochondrion, where they start the\u00a0<strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1805\">Krebs cycle<\/a> <\/strong>(also known as the Citric Acid Cycle). The reason this stage is considered a cycle is because a molecule called oxaloacetate is present at both the beginning and end of this reaction and is used to break down the two molecules of acetyl CoA.\u00a0 The reactions that occur next are shown in Figure 4.10.6.<\/p>\n<figure id=\"attachment_1809\" aria-describedby=\"caption-attachment-1809\" style=\"width: 835px\" class=\"wp-caption alignnone\"><img class=\"wp-image-1809\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/krebs-cycle-1.png\" alt=\"Image shows a diagram of the reactants and products of the Krebs Cycle. Two molecules of acetyl CoA are converted to 4 carbon dioxide which are released as cellular waste, 2 ATP which are used in the cell for energy, and 8 NADH and 2 FADH2, both of which travel to the ETS.\" width=\"835\" height=\"510\"><figcaption id=\"caption-attachment-1809\" class=\"wp-caption-text\"><em>Figure 4.10.6 Reactants and products of the Krebs Cycle.<\/em><\/figcaption><\/figure>\n<div>\n<p><span style=\"font-size: 1.424em;font-weight: bold\">Steps of the Krebs Cycle<\/span><\/p>\n<\/div>\n<p>The <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1805\">Krebs cycle<\/a> itself actually begins when acetyl-CoA combines with a four-carbon molecule called OAA (oxaloacetate) (see Figure 4.10.6). This produces citric acid, which has six carbon atoms. This is why the Krebs cycle is also called the citric acid cycle.<\/p>\n<p>After citric acid forms, it goes through a series of reactions that release energy. The energy is captured in molecules of NADH, ATP, and FADH<sub>2<\/sub>, another energy-carrying\u00a0coenzyme. Carbon dioxide is also released as a waste product of these reactions.<\/p>\n<p>The final step of the Krebs cycle <em>regenerates<\/em> OAA, the molecule that began the Krebs cycle. This molecule is needed for the next turn through the cycle. Two turns are needed because glycolysis produces <em>two<\/em> pyruvic acid molecules when it splits glucose.<\/p>\n<h2>Results of the Glycolysis, Transition Reaction and Krebs Cycle<\/h2>\n<p>After glycolysis, transition reaction, and the Krebs cycle, the glucose molecule has been broken down completely. All six of its carbon atoms have combined with oxygen to form carbon dioxide. The energy from its\u00a0chemical bonds\u00a0has been stored in a total of 16 energy-carrier molecules. These molecules are:<\/p>\n<ul>\n<li>4 ATP (2 from glycolysis, 2 from Krebs Cycle)<\/li>\n<li>12 NADH (2 from glycolysis, 2 from transition reaction, and 8 from Krebs cycle)<\/li>\n<li>2 FADH<sub>2 <\/sub>(both from the Krebs cycle)<\/li>\n<\/ul>\n<p>The events of cellular respiration up to this point are\u00a0<span style=\"font-size: 1em\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_993\">exergonic reactions<\/a><\/span><span style=\"text-align: initial;font-size: 1em\">- they are releasing energy that had been stored in the bonds of the glucose molecule.\u00a0 This energy will be transferred to the third and final stage of cellular respiration: the Electron Transport System, which is an <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_984\">endergonic reaction<\/a>.\u00a0 Using an exothermic reaction to power an endothermic reaction is known as <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1813\">energy coupling<\/a>.<\/span><\/p>\n<div>\n<h1>Cellular Respiration Stage III:\u00a0Electron Transport Chain<\/h1>\n<\/div>\n<figure id=\"attachment_1820\" aria-describedby=\"caption-attachment-1820\" style=\"width: 489px\" class=\"wp-caption alignright\"><img class=\"wp-image-1820\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/ETC-1.png\" alt=\"Image shows the reactants and products of the electron transport chain. In this stage, 32 adenosine diphosphate and 32 inorganic phosphates combine to form 32 ATP. In addition, hydrogen and oxygen combine to form 6 molecules of water.\" width=\"489\" height=\"277\"><figcaption id=\"caption-attachment-1820\" class=\"wp-caption-text\"><em>Figure 4.10.7. Reactants and products of the electron transport chain.<\/em><\/figcaption><\/figure>\n<p><span style=\"text-align: initial;font-size: 1em\"><span style=\"text-align: initial;font-size: 1em\">\u00a0ETC, the final stage in cellular respiration produces 32 ATP.\u00a0\u00a0<\/span><\/span>The Electron Transport Chain is the final stage of cellular respiration. In this stage, energy being transported by NADH and FADH<sub>2<\/sub>\u00a0is transferred to ATP.\u00a0 In addition, oxygen acts as the final proton acceptor for the hydrogens released from all the NADH and FADH<sub>2<\/sub>, forming water.\u00a0 Figure 4.10.8 shows the reactants and products of the ETC.<\/p>\n<h2>Transporting Electrons<\/h2>\n<p>The <strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1816\">Electron transport chain<\/a><\/strong> is the third stage of cellular respiration and is illustrated in Figure 4.10.8. During this stage, high-energy electrons are released from NADH and FADH<sub>2<\/sub>, and they move along electron-transport chains on the inner membrane of the mitochondrion.\u00a0An electron-transport chain is a series of molecules that transfer electrons from molecule to molecule by\u00a0chemical reactions. Some of the energy from the electrons is used to pump hydrogen ions (H ) across the inner membrane, from the matrix into the intermembrane space. This\u00a0ion\u00a0transfer creates an\u00a0<a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1817\">electrochemical gradient<\/a>\u00a0that drives the synthesis of <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1623\">ATP<\/a>.<\/p>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_1819\" aria-describedby=\"caption-attachment-1819\" style=\"width: 811px\" class=\"wp-caption aligncenter\"><img class=\"wp-image-1819\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/The_Electron_Transport_Chain-1.jpg\" alt=\"\" width=\"811\" height=\"558\"><figcaption id=\"caption-attachment-1819\" class=\"wp-caption-text\"><em>Figure 4.10.8 Electron-transport chains on the inner membrane of the mitochondrion carry out the last stage of cellular respiration.<\/em><\/figcaption><\/figure>\n<div>\n<p><span style=\"font-size: 1.424em;font-weight: bold\">Making ATP<\/span><\/p>\n<\/div>\n<p>As shown in Figure 4.10.8, the pumping of hydrogen ions across the inner membrane creates a greater concentration of the ions in the intermembrane space than in the matrix. This gradient causes the ions to flow back across the membrane into the matrix, where their concentration is lower. ATP synthase acts as a channel protein, helping the hydrogen ions cross the membrane. It also acts as an enzyme, forming ATP from ADP and inorganic phosphate in a process called oxidative phosphorylation. After passing through the electron-transport chain, the \u201cspent\u201d electrons combine with oxygen to form water.<\/p>\n<div>\n<h1>How Much ATP?<\/h1>\n<\/div>\n<p>You have seen how the three stages of <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1818\">aerobic respiration<\/a> use the energy in glucose to make <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1623\">ATP<\/a>. How much ATP is produced in all three stages combined? Glycolysis produces two ATP molecules, and the Krebs cycle produces two more. Electron transport begins with several molecules of NADH and FADH<sub>2<\/sub>\u00a0from the Krebs cycle and transfers their energy into as many as 34 more ATP molecules. All told, then, up to 38 molecules of ATP can be produced from just one molecule of glucose in the process of cellular respiration.<\/p>\n<div>\n<div class=\"textbox textbox--key-takeaways\">\n<header class=\"textbox__header\">\n<h1 class=\"textbox__title\"><span style=\"color: #ffffff\">4.10 Summary<\/span><\/h1>\n<\/header>\n<div class=\"textbox__content\">\n<ul>\n<li><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1172\">Cellular respiration<\/a> is the <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1796\">aerobic<\/a> process by which living cells break down <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_317\">glucose<\/a> molecules, release energy, and form molecules of <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1623\">ATP<\/a>.\u00a0Generally speaking, this three-stage process involves glucose and oxygen reacting to form carbon dioxide and\u00a0water.<\/li>\n<li>The first stage of cellular respiration, called glycolysis, takes place in the cytoplasm. In this step,\u00a0enzymes\u00a0split a molecule of glucose into two molecules of pyruvate, which releases energy that is transferred to ATP.\u00a0 Following glycolysis, a short reaction called the transition reaction converts the pyruvate into two molecules of acetyl CoA.<\/li>\n<li>The organelle called a mitochondrion is the site of the other two stages of cellular respiration. The mitochondrion has an inner and outer membrane separated by an intermembrane space, and the inner membrane encloses a space called the matrix.<\/li>\n<li>The second stage of cellular respiration, called the <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1805\">Krebs cycle<\/a>, takes place in the matrix of a mitochondrion. During this stage, two turns through the cycle result in all of the carbon atoms from the two pyruvate molecules forming carbon dioxide and the energy from their\u00a0chemical bonds\u00a0being stored in a total of 16 energy-carrying molecules (including two from glycolysis and two from transition reaction).<\/li>\n<li>The third and final stage of cellular respiration, called <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1816\">electron transport<\/a>, takes place on the inner membrane of the mitochondrion. Electrons are transported from molecule to molecule down an electron-transport chain. Some of the energy from the electrons is used to pump hydrogen ions\u00a0across the membrane, creating an\u00a0electrochemical gradient\u00a0that drives the synthesis of many more molecules of ATP.<\/li>\n<li>In all three stages of cellular respiration combined, as many as 38 molecules of ATP are produced from just one molecule of glucose.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<div class=\"textbox textbox--exercises\">\n<header class=\"textbox__header\">\n<h1 class=\"textbox__title\"><span style=\"color: #ffffff\">4.10 Review Questions<\/span><\/h1>\n<\/header>\n<div class=\"textbox__content\">\n<ol>\n<li>What is the purpose of cellular respiration? Provide a concise summary of the process.<\/li>\n<li>State what happens during glycolysis.<\/li>\n<li>Describe the structure of a mitochondrion.<\/li>\n<li>What molecule is present at both the beginning and end of the Krebs cycle?<\/li>\n<li>What happens during the electron transport stage of cellular respiration?<\/li>\n<li>How many molecules of ATP can be produced from one molecule of glucose during all three stages of cellular respiration combined?<\/li>\n<li>Do plants undergo cellular respiration? Why or why not?<\/li>\n<li>Explain why the process of cellular respiration described in this section is considered aerobic.<\/li>\n<li>Name three energy-carrying molecules involved in cellular respiration.<\/li>\n<li>\n<div id=\"h5p-26\">\n<div class=\"h5p-iframe-wrapper\"><iframe id=\"h5p-iframe-26\" class=\"h5p-iframe\" data-content-id=\"26\" style=\"height:1px\" src=\"about:blank\" frameBorder=\"0\" scrolling=\"no\" title=\"3.7 True\/False\"><\/iframe><\/div>\n<\/div>\n<\/li>\n<li>Which stage of aerobic cellular respiration produces the most ATP?<\/li>\n<li>\n<div id=\"h5p-25\">\n<div class=\"h5p-content\" data-content-id=\"25\"><\/div>\n<\/div>\n<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<div class=\"textbox textbox--examples\">\n<header class=\"textbox__header\">\n<h1 class=\"textbox__title\"><span style=\"color: #ffffff\">4.10 Explore More<\/span><\/h1>\n<\/header>\n<div class=\"textbox__content\">\n<p>https:\/\/www.youtube.com\/watch?time_continue=2&amp;amp;v=00jbG_cfGuQ&amp;amp;feature=emb_logo<\/p>\n<p style=\"text-align: center\">ATP &amp; Respiration: Crash Course Biology #7, CrashCourse, 2012.<\/p>\n<p>https:\/\/www.youtube.com\/watch?v=4Eo7JtRA7lg&amp;amp;t=3s<\/p>\n<p style=\"text-align: center\">Cellular Respiration and the Mighty Mitochondria, The Amoeba Sisters, 2014.<\/p>\n<\/div>\n<\/div>\n<h2>Attributions<\/h2>\n<p><strong>Figure 4.10.1<\/strong><\/p>\n<p><a href=\"https:\/\/unsplash.com\/photos\/bU7vx56Fn50\" rel=\"cc:attributionURL\">Smores<\/a> by <a href=\"https:\/\/unsplash.com\/@jruscello\">Jessica Ruscello<\/a> on <a href=\"https:\/\/unsplash.com\/\">Unsplash<\/a> is used under the <a class=\"ICezk _2GAZm _2WvKc\" href=\"https:\/\/unsplash.com\/license\">Unsplash License<\/a> (https:\/\/unsplash.com\/license).<\/p>\n<p><strong>Figure 4.10.2<\/strong><\/p>\n<p><a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:2509_Carbohydrate_Metabolism.jpg\" rel=\"cc:attributionURL\">Carbohydrate_Metabolism<\/a> by <a href=\"https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/24-2-carbohydrate-metabolism\">OpenStax College<\/a> on Wikimedia Commons is used under a <a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/deed.en\">CC BY 3.0<\/a> (https:\/\/creativecommons.org\/licenses\/by\/3.0) license.<\/p>\n<p><strong>Figure 4.10.3<\/strong><\/p>\n<p>Glycolysis by Christine Miller is used under a <a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" rel=\"license\">CC BY 4.0<\/a> (https:\/\/creativecommons.org\/licenses\/by\/4.0\/) license.<\/p>\n<p><strong>Figure 4.10.4<\/strong><\/p>\n<p>Transition Reaction by Christine Miller is used under a <a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" rel=\"license\">CC BY 4.0<\/a> (https:\/\/creativecommons.org\/licenses\/by\/4.0\/) license.<\/p>\n<p><strong>Figure 4.10.5<\/strong><\/p>\n<p><a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Animal_mitochondrion_diagram_en.svg\" rel=\"cc:attributionURL\">Mitochondrion<\/a>\u00a0by Mariana Ruiz Villarreal [<a title=\"User:LadyofHats\" href=\"https:\/\/commons.wikimedia.org\/wiki\/User:LadyofHats\">LadyofHats<\/a>] on Wikimedia Commons is released into the <a href=\"https:\/\/en.wikipedia.org\/wiki\/Public_domain\">public domain<\/a> (https:\/\/en.wikipedia.org\/wiki\/Public_domain).<\/p>\n<p><strong>Figure 4.10.6<\/strong><\/p>\n<p>Krebs cycle by Christine Miller is used under a <a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" rel=\"license\">CC BY 4.0<\/a> (https:\/\/creativecommons.org\/licenses\/by\/4.0\/) license.<\/p>\n<p><strong>Figure 4.10.7<\/strong><\/p>\n<p>Electron Transport Chain (ETC) by Christine Miller is used under a <a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" rel=\"license\">CC BY 4.0<\/a> (https:\/\/creativecommons.org\/licenses\/by\/4.0\/) license.<\/p>\n<p><strong>Figure 4.10.8<\/strong><\/p>\n<p><a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:2508_The_Electron_Transport_Chain.jpg\" rel=\"cc:attributionURL\">The_Electron_Transport_Chain<\/a> by <a href=\"https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/24-2-carbohydrate-metabolism\">OpenStax College<\/a> on Wikimedia Commons is used under a <a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/deed.en\">CC BY 3.0<\/a> (https:\/\/creativecommons.org\/licenses\/by\/3.0) license.<\/p>\n<\/div>\n<h2>References<\/h2>\n<p class=\"hanging-indent\">CrashCourse. (2012, March 12). ATP &amp; Respiration: Crash Course Biology #7. YouTube. https:\/\/www.youtube.com\/watch?time_continue=2&amp;amp;v=00jbG_cfGuQ&amp;amp;feature=emb_logo<\/p>\n<p class=\"hanging-indent\"><span class=\"os-title-label\"><span class=\"search-highlight text\" data-timestamp=\"1593971709033\" data-highlight-id=\"be4d62de-64ba-45d3-9e0a-94a6f01c99c3\" data-highlighted=\"true\"><span class=\"search-highlight text focus\" data-timestamp=\"1593971124968\" data-highlight-id=\"cf2748f4-996a-4532-916c-452da1001e7f\" data-highlighted=\"true\">Betts, J. G., Young, K.A., Wise, J.A., Johnson, E., Poe, B., Kruse, D.H., Korol, O., Johnson, J.E., Womble, M., DeSaix, P. (2013, April 25). <\/span>Figure\u00a0<\/span><\/span><span class=\"os-number\"><span class=\"search-highlight text\" data-timestamp=\"1593971709033\" data-highlight-id=\"be4d62de-64ba-45d3-9e0a-94a6f01c99c3\" data-highlighted=\"true\">24.8<\/span><\/span><span class=\"os-divider\">\u00a0<\/span><span id=\"15064\" class=\"os-title\" data-type=\"title\"><span class=\"search-highlight text\" data-timestamp=\"1593971709033\" data-highlight-id=\"be4d62de-64ba-45d3-9e0a-94a6f01c99c3\" data-highlighted=\"true\">Electron Transport Chain [digital image]<\/span><\/span><span class=\"os-caption\"><span class=\"search-highlight text last\" data-timestamp=\"1593971709033\" data-highlight-id=\"be4d62de-64ba-45d3-9e0a-94a6f01c99c3\" data-highlighted=\"true\">. In <em>Anatomy &amp; Physiology, Connexions<\/em> (Section ). OpenStax.\u00a0 https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/24-2-carbohydrate-metabolism<\/span><\/span><\/p>\n<p class=\"hanging-indent\"><span class=\"os-title-label\"><span class=\"search-highlight text focus\" data-timestamp=\"1593971124968\" data-highlight-id=\"cf2748f4-996a-4532-916c-452da1001e7f\" data-highlighted=\"true\">Betts, J. G., Young, K.A., Wise, J.A., Johnson, E., Poe, B., Kruse, D.H., Korol, O., Johnson, J.E., Womble, M., DeSaix, P. (2013, April 25). Figure <\/span><\/span><span class=\"os-number\"><span class=\"search-highlight text focus\" data-timestamp=\"1593971124968\" data-highlight-id=\"cf2748f4-996a-4532-916c-452da1001e7f\" data-highlighted=\"true\">24.9<\/span><\/span><span class=\"os-divider\">\u00a0<\/span><span id=\"83491\" class=\"os-title\" data-type=\"title\"><span class=\"search-highlight text focus\" data-timestamp=\"1593971124968\" data-highlight-id=\"cf2748f4-996a-4532-916c-452da1001e7f\" data-highlighted=\"true\">Carbohydrate Metabolism [digital image]<\/span><\/span><span class=\"os-caption\"><span class=\"search-highlight text last focus\" data-timestamp=\"1593971124968\" data-highlight-id=\"cf2748f4-996a-4532-916c-452da1001e7f\" data-highlighted=\"true\">. <\/span><\/span>In <em>Anatomy &amp; Physiology, Connexions<\/em> (Section 24.2). OpenStax.\u00a0 https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/24-2-carbohydrate-metabolism<\/p>\n<p class=\"hanging-indent\">The Amoeba Sisters. (2014, October 22). Cellular Respiration and the Mighty Mitochondria. YouTube. https:\/\/www.youtube.com\/watch?v=4Eo7JtRA7lg&amp;amp;t=3s<\/p>\n<p>&nbsp;<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_4380_5517\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_4380_5517\"><div tabindex=\"-1\"><p>Any reaction which requires or absorbs energy from its surroundings, usually in the form of heat.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_4380_5519\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_4380_5519\"><div tabindex=\"-1\"><p>The minimum energy required to cause a reaction to occur.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_4380_5547\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_4380_5547\"><div tabindex=\"-1\"><\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_4380_1009\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_4380_1009\"><div tabindex=\"-1\"><p>Created by CK-12 Foundation\/Adapted by Christine Miller<\/p>\n<figure id=\"attachment_1004\" aria-describedby=\"caption-attachment-1004\" style=\"width: 345px\" class=\"wp-caption aligncenter\"><img class=\"wp-image-1003\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2019\/06\/woman-in-black-tank-top-and-black-shorts-lying-on-floor-e1606261742472.jpg\" alt=\"A female gymnast performing a backbend with one leg extended up to the ceiling.\" width=\"345\" height=\"500\"><figcaption id=\"caption-attachment-1004\" class=\"wp-caption-text\"><em>Figure 11.6.1 That's quite a stretch!<\/em><\/figcaption><\/figure>\n<div>\n<h1>Double Jointed?<\/h1>\n<\/div>\n<p>Is this woman double jointed? No, there is actually no such thing \u2014 at least as far as humans are concerned. However, some people, like the woman pictured in Figure 11.6.1, are much more flexible than others, generally because they have looser ligaments. Physicians call this condition joint hypermobility. Regardless of what it\u2019s called, the feats of people with highly mobile joints can be quite impressive.<\/p>\n<div>\n<h1>What Are Joints?<\/h1>\n<\/div>\n<p><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_3949\"><strong>Joints<\/strong>\u00a0<\/a>are locations at which\u00a0bones\u00a0of the skeleton connect with one another. A joint is also called an articulation. The majority of joints are structured in such a way that they allow movement. However, not all joints allow movement. Of joints that\u00a0<em>do<\/em>\u00a0allow movement, the extent and direction of the movements they allow also vary.<\/p>\n<div>\n<h1>Classification\u00a0of Joints<\/h1>\n<\/div>\n<p>Joints can be classified structurally or functionally. The structural\u00a0classification\u00a0of joints depends on the manner in which the\u00a0bones\u00a0connect to each other. The functional classification of joints depends on the nature of the movement the joints allow. There is significant overlap between the two types of classifications, because function depends largely on structure.<\/p>\n<h2>Structural Classification of Joints<\/h2>\n<p>The structural classification of joints is based on the type of tissue that binds the\u00a0bones\u00a0to each other at the joint. There are three types of joints in the structural classification: fibrous, cartilaginous, and synovial joints.<\/p>\n<ol>\n<li><strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4084\">Fibrous joints<\/a><\/strong> are joints in which bones are joined by dense connective tissue that is rich in collagen fibres. These joints are also called sutures. The joints between bones of the cranium are fibrous joints.<\/li>\n<li><strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4085\">Cartilaginous joints<\/a><\/strong>\u00a0are joints in which bones are joined by cartilage. The joints between most of the vertebrae in the spine are cartilaginous joints.<\/li>\n<li><strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4086\">Synovial joints<\/a><\/strong> are characterized by a fluid-filled space (called a synovial cavity) between the bones of the joints. You can see a drawing of a typical synovial joint in Figure 11.6.2. The cavity is enclosed by a membrane and filled with a fluid (called synovial fluid) that provides extra cushioning to the ends of the bones. Cartilage covers the articulating surfaces of the two bones, but the bones are actually held together by ligaments. The knee is a synovial joint.<\/li>\n<\/ol>\n<figure id=\"attachment_1004\" aria-describedby=\"caption-attachment-1004\" style=\"width: 483px\" class=\"wp-caption aligncenter\"><img class=\"wp-image-1004\" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/Synovial_Joints.jpg\" alt=\"11.6.2 Synovial Joint\" width=\"483\" height=\"535\"><figcaption id=\"caption-attachment-1004\" class=\"wp-caption-text\"><em>Figure 11.6.2 A typical synovial joint is represented by this diagram.<\/em><\/figcaption><\/figure>\n<h2>Functional Classification of Joints<\/h2>\n<p>The functional classification of joints is based on the type and degree of movement that they allow. There are three types of joints in the functional classification: immovable, partly movable, and movable joints.<\/p>\n<ol>\n<li><strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4088\">Immovable joints<\/a><\/strong>\u00a0allow little or no movement at the joint. Most immovable joints are fibrous joints. Besides the bones of the cranium, immovable joints include joints between the tibia and fibula in the lower leg, and between the radius and ulna in the lower arm.<\/li>\n<li><strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4090\">Partly movable joints<\/a><\/strong>\u00a0permit slight movement. Most partly movable joints are cartilaginous joints. Besides the joints between vertebrae, they include the joints between the ribs and sternum (breast bone).<\/li>\n<li><strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_2194\">Movable joints<\/a><\/strong>\u00a0allow bones to move freely. All movable joints are synovial joints. Besides the knee, they include the shoulder, hip, and elbow. Movable joints are the most common type of joints in the body.<\/li>\n<\/ol>\n<h2>Types of Movable Joints<\/h2>\n<p>Movable joints can be classified further according to the type of movement they allow. There are six classes of movable joints: pivot, hinge, saddle, plane, condyloid, and ball-and-socket joints. An example of each class \u2014 as well as the type of movement it allows \u2014 is shown in Figure 11.6.3.<\/p>\n<div>\n<figure id=\"attachment_1007\" aria-describedby=\"caption-attachment-1007\" style=\"width: 985px\" class=\"wp-caption aligncenter\"><img class=\"wp-image-1007 \" src=\"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-content\/uploads\/sites\/152\/2023\/10\/Types_of_Synovial_Joints.jpg\" alt=\"11.6.3 Types of Synovial Joints\" width=\"985\" height=\"1174\"><figcaption id=\"caption-attachment-1007\" class=\"wp-caption-text\"><em>Figure 11.6.3 This diagram shows the six classes of movable joints in the human body. All of these joints are synovial joints.<\/em><\/figcaption><\/figure>\n<\/div>\n<ul>\n<li style=\"margin-top: 0px\">A\u00a0<strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4093\">ball-and-socket joint<\/a><\/strong> allows the greatest range of movement of any movable joint. It allows forward and backward motion, as well as upward and downward movement. It also allows rotation in a circle. The hip and shoulder are the only two ball-and-socket joints in the human body.<\/li>\n<li>A\u00a0<strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4094\">pivot joint<\/a><\/strong>\u00a0allows one bone to rotate around another. An example of a pivot joint is the joint between the first two vertebrae in the spine. This joint allows the head to rotate from left to right and back again.<\/li>\n<li>A\u00a0<strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4096\">hinge joint<\/a><\/strong>\u00a0allows back and forth movement like the hinge of a door. An example of a hinge joint is the elbow. This joint allows the arm to bend back and forth.<\/li>\n<li>A\u00a0<strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4098\">saddle joint<\/a><\/strong>\u00a0allows two different types of movement. An example of a saddle joint is the joint between the first metacarpal bone in the hand and one of the carpal bones in the wrist. This joint allows the thumb to move toward and away from the index finger, and also to cross over the palm toward the little finger.<\/li>\n<li>A\u00a0<strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4100\">plane joint<\/a><\/strong>\u00a0(also called a gliding joint) allows two bones\u00a0to\u00a0glide over one another. The joints between the tarsals in the ankles and between the carpals in the wrists are mainly gliding joints. In the wrist, this type of joint allows the hand to bend upward at the wrist, and also to wave from side to side while the lower arm is held steady.<\/li>\n<li>A\u00a0<strong><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1988\">condyloid joint<\/a><\/strong>\u00a0is one in which an oval-shaped head on one bone moves in an elliptical cavity in another bone, allowing movement in all directions, except rotation around an axis. The joint between the radius in the lower arm and carpal bones of the wrist is a condyloid joint, as is the joint at the\u00a0base\u00a0of the index finger.<\/li>\n<\/ul>\n<div>\n<h1>Feature: My\u00a0Human Body<\/h1>\n<\/div>\n<p>Of all the parts of the\u00a0skeletal system, the joints are generally the most fragile and subject to damage. If the cartilage that cushions bones at joints wears away, it does not grow back. Eventually, all of the cartilage may wear away. This causes <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4102\">osteoarthritis<\/a>, which can be both painful and debilitating. In serious cases of <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/osteoarthritis\/symptoms-causes\/syc-20351925\">osteoarthritis<\/a>, people may lose the ability to climb stairs, walk long distances, perform routine daily activities, or participate in activities they love, such as gardening or playing sports. If you protect your joints, you can reduce your chances of joint damage, pain, and disability. If you already have joint damage, it is equally important to protect your joints and limit further damage. Follow these five tips:<\/p>\n<ol>\n<li><strong>Maintain a normal, healthy<\/strong><strong>\u00a0<\/strong>weight<strong>.<\/strong>\u00a0The\u00a0more you weigh, the more force you exert on your joints. When you walk, each knee has to bear a force equal to as much as\u00a0<em>six times<\/em>\u00a0your body\u00a0weight. If a person weighs 200 pounds, each knee bears more than half a ton of weight with every step. Seven in ten knee replacement surgeries for osteoarthritis can be attributed to\u00a0obesity.<\/li>\n<li><strong>Avoid too much high-impact<\/strong><strong>\u00a0<\/strong>exercise<strong>.<\/strong>\u00a0Examples of high-impact activities include volleyball, basketball, and tennis. These activities generally involve running or jumping on hard surfaces, which puts tremendous stress on weight-bearing joints, especially the knees. Replace some or all of your high-impact activities with low-impact activities, such as biking, swimming, yoga, or lifting light weights.<\/li>\n<li><strong>Reduce your risk of injury.<\/strong>\u00a0Don\u2019t be a weekend warrior, sitting at a desk all week and then crowding all your physical activity into two days. Get involved in a regular, daily\u00a0exercise\u00a0routine that keeps your body fit and your\u00a0muscles\u00a0toned. Building up muscles will make your joints more stable, allowing stress to spread across them. Be sure to do some stretching every day to keep the muscles around joints flexible and less prone to injury.<\/li>\n<li><strong>Distribute work over your body, and use your largest, strongest joints.<\/strong>\u00a0Use your shoulder, elbow, and wrist to lift heavy objects \u2014 not just your fingers. Hold small items in the palm of your hand, rather than by the fingers. Carry heavy items in a backpack, rather than in your hands. Hold weighty objects close to your body, instead of at arms\u2019 length. Lift with your hips and knees, not your back.<\/li>\n<li><strong>Respect pain.<\/strong>\u00a0If it hurts, stop doing it. Take a break from the activity \u2014 at least until the pain stops. Try to use joints only to the point of mild fatigue, not pain.<\/li>\n<\/ol>\n<div>\n<div class=\"textbox textbox--key-takeaways\">\n<header class=\"textbox__header\">\n<h1 class=\"textbox__title\"><span style=\"color: #ffffff\">11.6 Summary<\/span><\/h1>\n<\/header>\n<div class=\"textbox__content\">\n<ul>\n<li><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_3949\">Joints<\/a>\u00a0are\u00a0spots\u00a0at which <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_2552\">bones<\/a>\u00a0of the skeleton connect with one another. A joint is also called an articulation.<\/li>\n<li>Joints can be classified structurally or functionally, and there is significant overlap between the two types of classifications.<\/li>\n<li>The structural classification of joints depends on the type of tissue that binds the bones to each other at the joint. There are three types of joints in the structural classification: <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4084\">fibrous<\/a>, <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4085\">cartilaginous<\/a>, and <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4086\">synovial joints<\/a>.<\/li>\n<li>The functional classification of joints is based on the type and degree of movement that they allow. There are three types of joints in the functional classification: <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4088\">immovable<\/a>, <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4090\">partly movable<\/a>, and <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_2194\">movable joints<\/a>.<\/li>\n<li>Movable joints can be classified further according to the type of movement they allow. There are six classes of movable joints: <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4094\">pivot<\/a>, <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4096\">hinge<\/a>, <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4098\">saddle<\/a>, <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4100\">plane<\/a>, <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_1988\">condyloid<\/a>, and <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_4380_4093\">ball-and-socket joints<\/a>.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"textbox textbox--exercises\">\n<header class=\"textbox__header\">\n<h1 class=\"textbox__title\"><span style=\"color: #ffffff\">11.6 Review Questions<\/span><\/h1>\n<\/header>\n<div class=\"textbox__content\">\n<ol>\n<li>What are joints?<\/li>\n<li>What are two ways that joints are commonly classified?<\/li>\n<li>\n<div id=\"h5p-205\">\n<div class=\"h5p-iframe-wrapper\"><iframe id=\"h5p-iframe-205\" class=\"h5p-iframe\" data-content-id=\"205\" style=\"height:1px\" src=\"about:blank\" frameBorder=\"0\" scrolling=\"no\" title=\"11.6 Quiz\"><\/iframe><\/div>\n<\/div>\n<\/li>\n<li>How are joints classified structurally?<\/li>\n<li>Describe the functional classification of joints.<\/li>\n<li>How are movable joints classified?<\/li>\n<li>Name the six classes of movable joints. Describe how they move and give an example of each.<\/li>\n<li>Which specific type of moveable joint do you think your knee joint is? Explain your reasoning.<\/li>\n<li>Explain the difference between cartilage in a cartilaginous joint and cartilage in a synovial joint.<\/li>\n<li>Why are fibrous joints immovable?<\/li>\n<li>What is the function of synovial fluid?<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<div class=\"textbox textbox--examples\">\n<header class=\"textbox__header\">\n<h1 class=\"textbox__title\"><span style=\"color: #ffffff\">11.6 Explore More<\/span><\/h1>\n<\/header>\n<div class=\"textbox__content\">\n<p>https:\/\/www.youtube.com\/watch?v=IjiKUmfaZr4<\/p>\n<p style=\"text-align: center\">Why do your knuckles pop? - Eleanor Nelsen, TED-Ed, 2015.<\/p>\n<p>https:\/\/www.youtube.com\/watch?v=FWsBm3hr3B0<\/p>\n<p style=\"text-align: center\">Why haven\u2019t we cured arthritis? - Kaitlyn Sadtler and Heather J. Faust, TED-Ed, 2019.<\/p>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<h2>Attributions<\/h2>\n<p><strong>Figure 11.6.1<\/strong><\/p>\n<p><a href=\"https:\/\/pixabay.com\/de\/photos\/sport-gymnastik-fitness-frau-3994082\/\" rel=\"cc:attributionURL\">Tags: Sports Gymnastics Fitness Woman Preparation<\/a> by <a href=\"https:\/\/pixabay.com\/de\/users\/nastya_gepp-3773230\/\">nastya_gepp<\/a> on <a href=\"http:\/\/pixabay.com\">Pixabay<\/a> is used under the <a href=\"https:\/\/pixabay.com\/de\/service\/license\/\">Pixabay License<\/a> (https:\/\/pixabay.com\/de\/service\/license\/).<\/p>\n<p><strong>Figure 11.6.2<\/strong><\/p>\n<p><a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:907_Synovial_Joints.jpg\" rel=\"cc:attributionURL\">Synovial_Joints<\/a> by <a href=\"https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/9-4-synovial-joints\">OpenStax College<\/a> on Wikimedia Commons is used under a <a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/deed.en\" rel=\"license\">CC BY 3.0 <\/a>(https:\/\/creativecommons.org\/licenses\/by\/3.0) license.<\/p>\n<p><strong>Figure 11.6.3<\/strong><\/p>\n<p><a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:909_Types_of_Synovial_Joints.jpg\" rel=\"cc:attributionURL\">Types_of_Synovial_Joints<\/a>\u00a0by <a href=\"https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/9-4-synovial-joints\">OpenStax College<\/a> on Wikimedia Commons is used under a <a href=\"https:\/\/creativecommons.org\/licenses\/by\/3.0\/deed.en\" rel=\"license\">CC BY 3.0 <\/a>(https:\/\/creativecommons.org\/licenses\/by\/3.0) license.<\/p>\n<h2>References<\/h2>\n<p class=\"hanging-indent\">Betts, J. G., Young, K.A., Wise, J.A., Johnson, E., Poe, B., Kruse, D.H., Korol, O., Johnson, J.E., Womble, M., DeSaix, P. (2013, June 19). <span class=\"os-title-label\"><span class=\"search-highlight text\" data-timestamp=\"1596567079410\" data-highlight-id=\"7e7717cd-fb93-47e2-a575-7a15a0811909\" data-highlighted=\"true\">Figure\u00a0<\/span><\/span><span class=\"os-number\"><span class=\"search-highlight text\" data-timestamp=\"1596567079410\" data-highlight-id=\"7e7717cd-fb93-47e2-a575-7a15a0811909\" data-highlighted=\"true\">9.8<\/span><\/span><span class=\"os-divider\">\u00a0<\/span><span id=\"30020\" class=\"os-title\" data-type=\"title\"><span class=\"search-highlight text\" data-timestamp=\"1596567079410\" data-highlight-id=\"7e7717cd-fb93-47e2-a575-7a15a0811909\" data-highlighted=\"true\">Synovial joints<\/span><\/span> [digital image].\u00a0 In <em>Anatomy and Physiology<\/em> (Section 9.4). OpenStax. https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/9-4-synovial-joints<\/p>\n<p class=\"hanging-indent\">Betts, J. G., Young, K.A., Wise, J.A., Johnson, E., Poe, B., Kruse, D.H., Korol, O., Johnson, J.E., Womble, M., DeSaix, P. (2013, June 19). Figure 9.10 Types of synovial joints [digital image].\u00a0 In <em>Anatomy and Physiology<\/em> (Section 9.4). OpenStax. https:\/\/openstax.org\/books\/anatomy-and-physiology\/pages\/9-4-synovial-joints<\/p>\n<p class=\"hanging-indent\">Mayo Clinic Staff. (n.d.). Osteoarthritis [online article]. MayoClinic.org. https:\/\/www.mayoclinic.org\/diseases-conditions\/osteoarthritis\/symptoms-causes\/syc-20351925<\/p>\n<p class=\"hanging-indent\">TED-Ed. (2015, May 5). Why do your knuckles pop? - Eleanor Nelsen. YouTube. https:\/\/www.youtube.com\/watch?v=IjiKUmfaZr4<\/p>\n<p class=\"hanging-indent\">TED-Ed. (2019, November 7). Why haven\u2019t we cured arthritis? - Kaitlyn Sadtler and Heather J. Faust. YouTube. https:\/\/www.youtube.com\/watch?v=FWsBm3hr3B0<\/p>\n<p>&nbsp;<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><\/div>","protected":false},"author":32,"menu_order":9,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":"cc-by-nc"},"chapter-type":[48],"contributor":[],"license":[55],"class_list":["post-4380","chapter","type-chapter","status-publish","hentry","chapter-type-numberless","license-cc-by-nc"],"part":4320,"_links":{"self":[{"href":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-json\/pressbooks\/v2\/chapters\/4380","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-json\/wp\/v2\/users\/32"}],"version-history":[{"count":3,"href":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-json\/pressbooks\/v2\/chapters\/4380\/revisions"}],"predecessor-version":[{"id":6373,"href":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-json\/pressbooks\/v2\/chapters\/4380\/revisions\/6373"}],"part":[{"href":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-json\/pressbooks\/v2\/parts\/4320"}],"metadata":[{"href":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-json\/pressbooks\/v2\/chapters\/4380\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-json\/wp\/v2\/media?parent=4380"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-json\/pressbooks\/v2\/chapter-type?post=4380"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-json\/wp\/v2\/contributor?post=4380"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.ccconline.org\/acchumanbio\/wp-json\/wp\/v2\/license?post=4380"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}